The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice
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Relationships between Rodent White Adipose Fat Pads and Human White Adipose Fat DepotsMultiple Effects of Growth Hormone in the Body: Is it Really the Hormone for Growth?Tissue-Specific GHR Knockout Mice: Metabolic PhenotypesDevelopments in our understanding of the effects of growth hormone on white adipose tissue from mice: implications to the clinic.The Role of the Growth Hormone/Insulin-Like Growth Factor System in Visceral Adiposity.Minireview: mechanisms of growth hormone-mediated gene regulation.Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-α, and IL-1βDisruption of JAK2 in adipocytes impairs lipolysis and improves fatty liver in mice with elevated GH.Diminished mTOR signaling: a common mode of action for endocrine longevity factors.Differential impact of selective GH deficiency and endogenous GH excess on insulin-mediated actions in muscle and liver of male mice.DLK1/PREF1 regulates nutrient metabolism and protects from steatosis.Evolution of hepatic steatosis to fibrosis and adenoma formation in liver-specific growth hormone receptor knockout miceExpression of apoptosis-related genes in liver-specific growth hormone receptor gene-disrupted mice is sex dependentRegulation of mTOR activity in Snell dwarf and GH receptor gene-disrupted mice.Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver.Ames hypopituitary dwarf mice demonstrate imbalanced myelopoiesis between bone marrow and spleenGrowth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult MiceRemoval of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/- mice.The somatotropic axis and aging: Benefits of endocrine defects.Targeted deletion of growth hormone (GH) receptor in macrophage reveals novel osteopontin-mediated effects of GH on glucose homeostasis and insulin sensitivity in diet-induced obesityHepatic PPARγ Is Not Essential for the Rapid Development of Steatosis After Loss of Hepatic GH Signaling, in Adult Male MiceCardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice.Direct and indirect effects of growth hormone receptor ablation on liver expression of xenobiotic metabolizing genesAge-related and depot-specific changes in white adipose tissue of growth hormone receptor-null mice.Evaluation of growth hormone (GH) action in mice: discovery of GH receptor antagonists and clinical indications.Adipocyte JAK2 mediates growth hormone-induced hepatic insulin resistanceAltered somatotroph feedback regulation improves metabolic efficiency and limits adipose deposition in male mice.Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profilesThe GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerations.Adipocyte-specific deficiency of Janus kinase (JAK) 2 in mice impairs lipolysis and increases body weight, and leads to insulin resistance with ageing.Healthspan and longevity can be extended by suppression of growth hormone signaling.Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice.Impact of Growth Hormone on Regulation of Adipose Tissue.Increased fibrosis: A novel means by which GH influences white adipose tissue function.Altered structure and function of adipose tissue in long-lived mice with growth hormone-related mutations.The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects.Growth hormone controls lipolysis by regulation of FSP27 expression
P2860
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P2860
The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice
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2013 nî lūn-bûn
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2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
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2013年论文
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name
The role of GH in adipose tiss ...... H receptor gene-disrupted mice
@ast
The role of GH in adipose tiss ...... H receptor gene-disrupted mice
@en
type
label
The role of GH in adipose tiss ...... H receptor gene-disrupted mice
@ast
The role of GH in adipose tiss ...... H receptor gene-disrupted mice
@en
prefLabel
The role of GH in adipose tiss ...... H receptor gene-disrupted mice
@ast
The role of GH in adipose tiss ...... H receptor gene-disrupted mice
@en
P2093
P2860
P356
P1476
The role of GH in adipose tiss ...... H receptor gene-disrupted mice
@en
P2093
Andrzej Bartke
Bruce Kelder
Clare Vesel
Darlene E Berryman
Edward O List
Elahu S Gosney
Ellen R Lubbers
John J Kopchick
P2860
P304
P356
10.1210/ME.2012-1330
P577
2013-01-24T00:00:00Z