Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells.
about
Mechanisms of change in gene copy numberChromosomal instability at common fragile sites in Seckel syndromeStably transfected common fragile site sequences exhibit instability at ectopic sites.ATR preferentially interacts with common fragile site FRA3B and the binding requires its kinase activity in response to aphidicolin treatment.Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakageColour thresholding in video imaging.High-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1, that is amplified and overexpressed in oral cancer cells.Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells.Profiling breast cancer by array CGH.How a replication origin and matrix attachment region accelerate gene amplification under replication stress in mammalian cells.Impact of transforming viruses on cellular mutagenesis, genome stability, and cellular transformation.The role of fragile sites in sporadic papillary thyroid carcinomaSelective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S phase.Redox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunitiesEvidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon.Characterization at nucleotide resolution of the homogeneously staining region sites of insertion in two cancer cell lines.Requirement of wild-type p53 protein for maintenance of chromosomal integrity.Genome position and gene amplificationPlasmodium falciparum pfmdr1 amplification, mefloquine resistance, and parasite fitness.Enhanced flexibility and aphidicolin-induced DNA breaks near mammalian replication origins: implications for replicon mapping and chromosome fragility.Genomic instability driven by the human T-cell leukemia virus type I (HTLV-I) oncoprotein, Tax.Intrachromosomal telomere-like DNA sequences in Chinese hamster.An FHIT tumor suppressor gene?Identification of transgene integration loci of different highly expressing recombinant CHO cell lines by FISH.Shaping of tumor and drug-resistant genomes by instability and selection.
P2860
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P2860
Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Chromosome breakage at a major ...... multidrug-resistant CHO cells.
@ast
Chromosome breakage at a major ...... multidrug-resistant CHO cells.
@en
type
label
Chromosome breakage at a major ...... multidrug-resistant CHO cells.
@ast
Chromosome breakage at a major ...... multidrug-resistant CHO cells.
@en
prefLabel
Chromosome breakage at a major ...... multidrug-resistant CHO cells.
@ast
Chromosome breakage at a major ...... multidrug-resistant CHO cells.
@en
P2093
P2860
P356
P1476
Chromosome breakage at a major ...... multidrug-resistant CHO cells.
@en
P2093
P2860
P304
P356
10.1128/MCB.14.8.5202
P407
P577
1994-08-01T00:00:00Z