Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells.
about
Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3Inverted repeats as genetic elements for promoting DNA inverted duplication: implications in gene amplificationTelomere dysfunction and chromosome instabilityAmplification and expression of the ABC transporters ARA and MRP in a series of multidrug-resistant leukaemia cell sublinesAmplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaksMurine pancreatic tumor cell line TD2 bears the characteristic pattern of genetic changes with two independently amplified gene loci.On the mechanism of gene amplification induced under stress in Escherichia coliIntrachromosomal triplication of 15q11-q13.A novel gene amplification system in yeast based on double rolling-circle replication.Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakageSuppression of gene amplification and chromosomal DNA integration by the DNA mismatch repair systemAtm inactivation results in aberrant telomere clustering during meiotic prophase.Altered telomere nuclear matrix interactions and nucleosomal periodicity in ataxia telangiectasia cells before and after ionizing radiation treatmentThe effects of insertions on mammalian intrachromosomal recombinationHigh-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1, that is amplified and overexpressed in oral cancer cells.Telomere dynamics in an immortal human cell line.Short inverted repeats initiate gene amplification through the formation of a large DNA palindrome in mammalian cells.Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells.Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cellsDifferent roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells.DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line.The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line.Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells.Double rolling circle replication (DRCR) is recombinogenic.Gene amplification system based on double rolling-circle replication as a model for oncogene-type amplification.Intrastrand annealing leads to the formation of a large DNA palindrome and determines the boundaries of genomic amplification in human cancerAssessment of palindromes as platforms for DNA amplification in breast cancerChromosomal instability in oral cancer cells.Ontogeny of Unstable Chromosomes Generated by Telomere Error in Budding Yeast.The Genome Health Clinic and Genome Health Nutrigenomics concepts: diagnosis and nutritional treatment of genome and epigenome damage on an individual basis.Palindrome resolution and recombination in the mammalian germ line.Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells.Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon.Chromosomal instability and cytoskeletal defects in oral cancer cells.Characterization at nucleotide resolution of the homogeneously staining region sites of insertion in two cancer cell lines.Mechanisms underlying mutational signatures in human cancers.From Mutational Mechanisms in Single Cells to Mutational Patterns in Cancer Genomes.Telomeres in cancer: tumour suppression and genome instability.Rapid construction of transgene-amplified CHO cell lines by cell cycle checkpoint engineering.Inactivation of 14-3-3sigma influences telomere behavior and ionizing radiation-induced chromosomal instability.
P2860
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P2860
Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells.
description
1993 nî lūn-bûn
@nan
1993 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Sister chromatid fusion initia ...... gene in Chinese hamster cells.
@ast
Sister chromatid fusion initia ...... gene in Chinese hamster cells.
@en
type
label
Sister chromatid fusion initia ...... gene in Chinese hamster cells.
@ast
Sister chromatid fusion initia ...... gene in Chinese hamster cells.
@en
prefLabel
Sister chromatid fusion initia ...... gene in Chinese hamster cells.
@ast
Sister chromatid fusion initia ...... gene in Chinese hamster cells.
@en
P2093
P356
P1433
P1476
Sister chromatid fusion initia ...... gene in Chinese hamster cells.
@en
P2093
P304
P356
10.1101/GAD.7.4.605
P577
1993-04-01T00:00:00Z