CHEK2 variants associate with hereditary prostate cancer.
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Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individualsFrequency of CHEK2 mutations in a population based, case-control study of breast cancer in young womenThe CHEK2 gene and inherited breast cancer susceptibilityPALB2 variants in hereditary and unselected Finnish prostate cancer cases.Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant.Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancerThe checkpointkinase 2 (CHK2) 1100delC germ line mutation is not associated with the development of squamous cell carcinoma of the head and neck (SCCHN).CHEK2 is a multiorgan cancer susceptibility gene.CHEK2 (∗) 1100delC Mutation and Risk of Prostate Cancer.Germline CHEK2 mutations and colorectal cancer risk: different effects of a missense and truncating mutations?Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.A risk of essential thrombocythemia in carriers of constitutional CHEK2 gene mutationsSegregation analysis of 1,546 prostate cancer families in Finland shows recessive inheritance.ARLTS1 germline variants and the risk for breast, prostate, and colorectal cancerRapid Detection Method for the Four Most Common CHEK2 Mutations Based on Melting Profile AnalysisCHEK2 mutation and risk of prostate cancer: a systematic review and meta-analysis.An inherited NBN mutation is associated with poor prognosis prostate cancerATM polymorphisms as risk factors for prostate cancer development.A large germline deletion in the Chek2 kinase gene is associated with an increased risk of prostate cancer.In vitro phosphorylation of BRCA2 by the checkpoint kinase CHEK2.A personalised approach to prostate cancer screening based on genotyping of risk founder allelesAnalysis of the gene coding for the BRCA2-interacting protein PALB2 in hereditary prostate cancer.A multicenter study of cancer incidence in CHEK2 1100delC mutation carriersSelected aspects of inherited susceptibility to prostate cancer and tumours of different site of origin.Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.Multiple primary cancers as a guide to heritability.Hereditary breast cancer syndromes and genetic testing.Conflicting Interpretation of Genetic Variants and Cancer Risk by Commercial Laboratories as Assessed by the Prospective Registry of Multiplex Testing.Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin.Germline copy number variation analysis in Finnish families with hereditary prostate cancer.Pilot study on low penetrance breast and colorectal cancer predisposition markers in latvia.CHEK2 I157T associates with familial and sporadic colorectal cancer.The G84E mutation in the HOXB13 gene is associated with an increased risk of prostate cancer in Poland.Correlation of CHEK2 protein expression and c.1100delC mutation status with tumor characteristics among unselected breast cancer patients.Alternative splicing and mutation status of CHEK2 in stage III breast cancer.Prostate Cancer Genomics: Recent Advances and the Prevailing Underrepresentation from Racial and Ethnic Minorities.Targeted next generation sequencing identifies functionally deleterious germline mutations in novel genes in early-onset/familial prostate cancer.CHEK2 mutations and the risk of papillary thyroid cancer.Irrelevance of CHEK2 variants to diagnosis of breast/ovarian cancer predisposition in Polish cohort.CHEK2*1100delC is not an important high-risk gene in families with hereditary prostate cancer in southern Sweden.
P2860
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P2860
CHEK2 variants associate with hereditary prostate cancer.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
CHEK2 variants associate with hereditary prostate cancer.
@ast
CHEK2 variants associate with hereditary prostate cancer.
@en
type
label
CHEK2 variants associate with hereditary prostate cancer.
@ast
CHEK2 variants associate with hereditary prostate cancer.
@en
prefLabel
CHEK2 variants associate with hereditary prostate cancer.
@ast
CHEK2 variants associate with hereditary prostate cancer.
@en
P2093
P2860
P356
P1476
CHEK2 variants associate with hereditary prostate cancer.
@en
P2093
Matikainen MP
Schleutker J
Seppälä EH
Tammela TL
P2860
P2888
P304
P356
10.1038/SJ.BJC.6601425
P407
P577
2003-11-01T00:00:00Z
P5875
P6179
1052868427