The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching.
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Semaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1Extracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning.A systems biology view of blood vessel growth and remodellingThe RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin ContractilityTopography of extracellular matrix mediates vascular morphogenesis and migration speeds in angiogenesisSecretion of soluble vascular endothelial growth factor receptor 1 (sVEGFR1/sFlt1) requires Arf1, Arf6, and Rab11 GTPasesIncreased expression of angiogenic genes in the brains of mouse meg3-null embryosThe cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veinsLocal guidance of emerging vessel sprouts requires soluble Flt-1Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formationComputational modeling of interacting VEGF and soluble VEGF receptor concentration gradients.A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use.A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trapChanges in the cochlear vasculature and vascular endothelial growth factor and its receptors in the aging c57 mouse cochlea.Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.Excess centrosomes disrupt endothelial cell migration via centrosome scattering.Micron-scale spatially patterned, covalently immobilized vascular endothelial growth factor on hydrogels accelerates endothelial tubulogenesis and increases cellular angiogenic responsesNotch regulates the angiogenic response via induction of VEGFR-1.Regulation of angiogenesis by histone chaperone HIRA-mediated incorporation of lysine 56-acetylated histone H3.3 at chromatin domains of endothelial genes.Dynamic alterations in decoy VEGF receptor-1 stability regulate angiogenesis.Endothelial cell activation in a VEGF-A gradient: relevance to cell fate decisions.Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signalingpTransgenesis: a cross-species, modular transgenesis resource.Angiogenic factor signaling regulates centrosome duplication in endothelial cells of developing blood vesselsHypoxia influences the vascular expansion and differentiation of embryonic stem cell cultures through the temporal expression of vascular endothelial growth factor receptors in an ARNT-dependent manner.Design of growth factor sequestering biomaterialsAccelerated coronary angiogenesis by vegfr1-knockout endocardial cells.Flt-1 regulates vascular endothelial cell migration via a protein tyrosine kinase-7-dependent pathway.Notch signals in the endothelium and cancer "stem-like" cells: opportunities for cancer therapy.BMP9/ALK1 inhibits neovascularization in mouse models of age-related macular degeneration.VEGF-directed blood vessel patterning: from cells to organism.Oral metformin treatment prevents enhanced insulin demand and placental dysfunction in the pregnant rat fed a fructose-rich dietMicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling.Autocrine functions of VEGF in breast tumor cells: adhesion, survival, migration and invasion.MicroRNA control of vascular endothelial growth factor signaling output during vascular development.Both Kdr and Flt1 play a vital role in hypoxia-induced Src-PLD1-PKCγ-cPLA(2) activation and retinal neovascularizationPhotoreceptor avascular privilege is shielded by soluble VEGF receptor-1.Vascular endothelial growth factor promotes anatomical and functional recovery of injured peripheral nerves in the avascular cornea.TNFSF15 inhibits vasculogenesis by regulating relative levels of membrane-bound and soluble isoforms of VEGF receptor 1Production of VEGF receptor 1 and 2 mRNA and protein during endochondral bone repair is differential and healing phase specific.
P2860
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P2860
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching.
@ast
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching.
@en
type
label
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching.
@ast
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching.
@en
prefLabel
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching.
@ast
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching.
@en
P2093
P2860
P356
P1476
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching
@en
P2093
Brian H Annex
Cam Patterson
Gefei Zeng
Joseph B Kearney
Kimberly G Kallianos
Nicholas C Kappas
Surovi Hazarika
Victoria L Bautch
P2860
P304
P356
10.1083/JCB.200709114
P407
P577
2008-05-26T00:00:00Z