Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling.
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Effects of Oxidative Stress on Mesenchymal Stem Cell BiologyMechanisms of Vascular Calcification: The Pivotal Role of Pyruvate Dehydrogenase Kinase 4Cellular and Molecular Mechanisms of Chronic Kidney Disease with Diabetes Mellitus and Cardiovascular Diseases as Its ComorbiditiesRUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progressionRegulatory circuits controlling vascular cell calcificationArterial calcification in chronic kidney disease: key roles for calcium and phosphateHeterotopic mineralization (ossification or calcification) in tendinopathy or following surgical tendon traumaIn vitro models of aortic valve calcification: solidifying a systemMolecular and cellular aspects of calcific aortic valve diseaseSodium thiosulfate ameliorates oxidative stress and preserves renal function in hyperoxaluric ratsTxnip ablation reduces vascular smooth muscle cell inflammation and ameliorates atherosclerosis in apolipoprotein E knockout miceTranscription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes Mellitus.Redox signaling in cardiovascular pathophysiology: A focus on hydrogen peroxide and vascular smooth muscle cellsMolecular Mechanisms of Vascular Calcification in Chronic Kidney Disease: The Link between Bone and the VasculatureHarmful effects of the azathioprine metabolite 6-mercaptopurine in vascular cells: induction of mineralizationLupin protein isolate and cysteine-supplemented casein reduce calcification of atherosclerotic lesions in apoE-deficient mice.Calcific aortic valve stenosis: methods, models, and mechanismsA dynamic model of calcific nodule destabilization in response to monocyte- and oxidized lipid-induced matrix metalloproteinases.Vascular Calcification: Current Genetics Underlying This Complex Phenomenon.Activation of AKT by O-linked N-acetylglucosamine induces vascular calcification in diabetes mellitusIn vitro screening for β-hydroxy-β-methylglutaryl-CoA reductase inhibitory and antioxidant activity of sequentially extracted fractions of Ficus palmata Forsk.High mobility group box 1 induces calcification of aortic valve interstitial cells via toll-like receptor 4.Inflammation and the osteogenic regulation of vascular calcification: a review and perspective.Focal induction of ROS-release to trigger local vascular degenerationAntioxidant enzymes reduce DNA damage and early activation of valvular interstitial cells in aortic valve sclerosis.Dipeptidyl peptidase-4 inhibitor gemigliptin protects against vascular calcification in an experimental chronic kidney disease and vascular smooth muscle cells.Farnesoid X receptor activation prevents the development of vascular calcification in ApoE-/- mice with chronic kidney disease.Synergism between Wnt3a and heparin enhances osteogenesis via a phosphoinositide 3-kinase/Akt/RUNX2 pathway.RANKL up-regulates brain-type creatine kinase via poly(ADP-ribose) polymerase-1 during osteoclastogenesis.Calcific aortic valve disease: a consensus summary from the Alliance of Investigators on Calcific Aortic Valve Disease.Evidence for active regulation of pro-osteogenic signaling in advanced aortic valve disease.The molecular biology and pathophysiology of vascular calcification.Reactive oxygen species, inflammation and calcium oxalate nephrolithiasis.Targeted reduction of vascular Msx1 and Msx2 mitigates arteriosclerotic calcification and aortic stiffness in LDLR-deficient mice fed diabetogenic diets.Advanced glycation end products accelerate rat vascular calcification through RAGE/oxidative stress.Arterial injury promotes medial chondrogenesis in Sm22 knockout mice.Vascular remodeling and arterial calcification are directly mediated by S100A12 (EN-RAGE) in chronic kidney disease.Inhibition of FOXO1/3 promotes vascular calcificationInhibition of bone morphogenetic protein signal transduction prevents the medial vascular calcification associated with matrix Gla protein deficiency.Runx2-upregulated receptor activator of nuclear factor κB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages.
P2860
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P2860
Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Oxidative stress induces vascu ...... factor Runx2 by AKT signaling.
@ast
Oxidative stress induces vascu ...... factor Runx2 by AKT signaling.
@en
type
label
Oxidative stress induces vascu ...... factor Runx2 by AKT signaling.
@ast
Oxidative stress induces vascu ...... factor Runx2 by AKT signaling.
@en
prefLabel
Oxidative stress induces vascu ...... factor Runx2 by AKT signaling.
@ast
Oxidative stress induces vascu ...... factor Runx2 by AKT signaling.
@en
P2093
P2860
P356
P1476
Oxidative stress induces vascu ...... factor Runx2 by AKT signaling
@en
P2093
Chang Hyun Byon
Jay M McDonald
John C Kappes
Thomas L Clemens
Victor M Darley-Usmar
Yabing Chen
P2860
P304
15319-15327
P356
10.1074/JBC.M800021200
P407
P50
P577
2008-03-31T00:00:00Z