AP214, an analogue of alpha-melanocyte-stimulating hormone, ameliorates sepsis-induced acute kidney injury and mortality.
about
The melanocortin MC(1) receptor agonist BMS-470539 inhibits leucocyte trafficking in the inflamed vasculatureSynchronous recruitment of epigenetic modifiers to endotoxin synergistically activated Tnf-α gene in acute kidney injuryEffects of continuous erythropoietin receptor activator in sepsis-induced acute kidney injury and multi-organ dysfunctionAnimal models of sepsis and sepsis-induced kidney injuryMelanocortin-1 Receptor Polymorphisms and the Risk of Complicated Sepsis After Trauma: A Candidate Gene Association Study.The melanocortin agonist AP214 exerts anti-inflammatory and proresolving propertiesHemodynamic changes in the kidney in a pediatric rat model of sepsis-induced acute kidney injury.Sirt1 deletion leads to enhanced inflammation and aggravates endotoxin-induced acute kidney injuryCalpastatin controls polymicrobial sepsis by limiting procoagulant microparticle releaseHigh-dose ascorbate with low-dose amphotericin B attenuates severity of disease in a model of the reappearance of candidemia during sepsis in the mouse.Cecal ligation puncture procedure.Development of oxidative stress in the peritubular capillary microenvironment mediates sepsis-induced renal microcirculatory failure and acute kidney injury.Chronic kidney disease worsens sepsis and sepsis-induced acute kidney injury by releasing High Mobility Group Box Protein-1Development of intestinal ischemia/reperfusion-induced acute kidney injury in rats with or without chronic kidney disease: Cytokine/chemokine response and effect of α-melanocyte-stimulating hormone.Experimental evidence that preexisting chronic kidney disease is a risk factor for acute kidney injurySesamol ameliorates hypotension by modulating cytokines and PPAR-gamma in systemic inflammatory responseAdrenocorticotropic hormone ameliorates acute kidney injury by steroidogenic-dependent and -independent mechanismsA two-hit mechanism for sepsis-induced impairment of renal tubule functionCurbing Inflammation through Endogenous Pathways: Focus on Melanocortin PeptidesUse of Biotelemetry to Define Physiology-Based Deterioration Thresholds in a Murine Cecal Ligation and Puncture Model of Sepsis.Methyl-2-acetamidoacrylate, an ethyl pyruvate analog, decreases sepsis-induced acute kidney injury in mice.Pre-existing renal disease promotes sepsis-induced acute kidney injury and worsens outcomeReduced production of creatinine limits its use as marker of kidney injury in sepsisABT-719 for the Prevention of Acute Kidney Injury in Patients Undergoing High-Risk Cardiac Surgery: A Randomized Phase 2b Clinical Trial.Class B scavenger receptor types I and II and CD36 targeting improves sepsis survival and acute outcomes in mice.Renoprotective approaches and strategies in acute kidney injuryNeuropeptide receptors as potential drug targets in the treatment of inflammatory conditionsLeveraging melanocortin pathways to treat glomerular diseases.Clinical and Experimental Sepsis Impairs CD8 T-Cell-Mediated Immunity.Mediators of inflammation in acute kidney injury.Osthole protects sepsis-induced acute kidney injury via down-regulating NF-κB signal pathway.Challenges and advances in the treatment of AKI.Pharmacological targets in the renal peritubular microenvironment: implications for therapy for sepsis-induced acute kidney injury.Direct and indirect antimicrobial activities of neuropeptides and their therapeutic potential.Designing drugs that combat kidney damage.Recent early clinical drug development for acute kidney injury.Alpha-melanocyte stimulating hormone ameliorates disease activity in an induced murine lupus-like model.Enhanced Cationic Charge is a Key Factor in Promoting Staphylocidal Activity of α-Melanocyte Stimulating Hormone via Selective Lipid Affinity.Inhibition of NF-kappaB ameliorates sepsis-induced downregulation of aquaporin-2/V2 receptor expression and acute renal failure in vivo.Neuropeptide downregulation in sepsis.
P2860
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P2860
AP214, an analogue of alpha-melanocyte-stimulating hormone, ameliorates sepsis-induced acute kidney injury and mortality.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
AP214, an analogue of alpha-me ...... e kidney injury and mortality.
@ast
AP214, an analogue of alpha-me ...... e kidney injury and mortality.
@en
type
label
AP214, an analogue of alpha-me ...... e kidney injury and mortality.
@ast
AP214, an analogue of alpha-me ...... e kidney injury and mortality.
@en
prefLabel
AP214, an analogue of alpha-me ...... e kidney injury and mortality.
@ast
AP214, an analogue of alpha-me ...... e kidney injury and mortality.
@en
P2093
P2860
P356
P1433
P1476
AP214, an analogue of alpha-me ...... e kidney injury and mortality.
@en
P2093
A Leelahavanichkul
J Frøkiaer
J Schnermann
P S T Yuen
T E N Jonassen
P2860
P2888
P304
P356
10.1038/KI.2008.97
P407
P577
2008-03-19T00:00:00Z