SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin.
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MCC inhibits beta-catenin transcriptional activity by sequestering DBC1 in the cytoplasmInflammation and intracellular metabolism: new targets in OAControlling Redox Status for Stem Cell Survival, Expansion, and DifferentiationSirtuins in epigenetic regulationHigh SIRT1 expression is a negative prognosticator in pancreatic ductal adenocarcinomaSIRT2 interacts with β-catenin to inhibit Wnt signaling output in response to radiation-induced stressEnterocyte-specific inactivation of SIRT1 reduces tumor load in the APC(+/min) mouse model.SIRT1 is a positive regulator of the master osteoblast transcription factor, RUNX2.Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells.Sirtuin1 (Sirt1) promotes cortical bone formation by preventing β-catenin sequestration by FoxO transcription factors in osteoblast progenitors.Sirtuin 1 is a negative regulator of parathyroid hormone stimulation of matrix metalloproteinase 13 expression in osteoblastic cells: role of sirtuin 1 in the action of PTH on osteoblasts.Curtailing endothelial TGF-β signaling is sufficient to reduce endothelial-mesenchymal transition and fibrosis in CKDThe Sirt1 Activators SRT2183 and SRT3025 Inhibit RANKL-Induced Osteoclastogenesis in Bone Marrow-Derived Macrophages and Down-Regulate Sirt3 in Sirt1 Null CellsEpigenetic Control of Stem Cell Potential during Homeostasis, Aging, and DiseaseSensitization of chemo-resistant human chronic myeloid leukemia stem-like cells to Hsp90 inhibitor by SIRT1 inhibition.Histone Deacetylases in Bone Development and Skeletal Disorders.SIRT1 inhibits adipogenesis and promotes myogenic differentiation in C3H10T1/2 pluripotent cells by regulating Wnt signaling.ING1b negatively regulates HIF1α protein levels in adipose-derived stromal cells by a SUMOylation-dependent mechanismSirtuins Function as the Modulators in Aging-related Diseases in Common or RespectivelyExpression and clinical significance of Sirt1 in colorectal cancer.Sirt1 is involved in decreased bone formation in aged apolipoprotein E-deficient mice.PTH Signaling and Epigenetic Control of Bone Remodeling.Acetylation reduces SOX9 nuclear entry and ACAN gene transactivation in human chondrocytes.Resveratrol Exerts Dosage-Dependent Effects on the Self-Renewal and Neural Differentiation of hUC-MSCs.GCN5 modulates osteogenic differentiation of periodontal ligament stem cells through DKK1 acetylation in inflammatory microenvironment.SIRT1 increases YAP- and MKK3-dependent p38 phosphorylation in mouse liver and human hepatocellular carcinoma.Mesenchymal stem cell aging: Mechanisms and influences on skeletal and non-skeletal tissues.Nicotinamide Promotes Adipogenesis in Umbilical Cord-Derived Mesenchymal Stem Cells and Is Associated with Neonatal Adiposity: The Healthy Start BabyBUMP ProjectMesenchymal stem cells with Sirt1 overexpression suppress breast tumor growth via chemokine-dependent natural killer cells recruitment.Adipose tissue NAD+-homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health.SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress.SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro.The interaction between acetylation and serine-574 phosphorylation regulates the apoptotic function of FOXO3.Bone cell senescence: mechanisms and perspectives.Intractable diseases treated with intra-bone marrow-bone marrow transplantationOsteoblast dysfunctions in bone diseases: from cellular and molecular mechanisms to therapeutic strategies.Chromatin modifiers and histone modifications in bone formation, regeneration, and therapeutic intervention for bone-related disease.Mitochondrial metabolic failure in telomere attrition-provoked aging of bone marrow mesenchymal stem cells.Stem Cells in Skeletal Tissue Engineering: Technologies and Models.Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction.
P2860
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P2860
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin.
@ast
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin.
@en
type
label
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin.
@ast
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin.
@en
prefLabel
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin.
@ast
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin.
@en
P2093
P2860
P356
P1476
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin
@en
P2093
David B Sykes
David Scadden
Ernestina Schipani
Kayvan Zainabadi
Leonard Guarente
Petra Simic
Roland Baron
P2860
P304
P356
10.1002/EMMM.201201606
P577
2013-01-30T00:00:00Z