The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation
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Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transductionScatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptorRON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSPAutophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60srcCrystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252aMet receptor tyrosine kinase: enhanced signaling through adapter proteinsMET receptor tyrosine kinase controls dendritic complexity, spine morphogenesis, and glutamatergic synapse maturation in the hippocampusNeuronal connectivity as a convergent target of gene × environment interactions that confer risk for Autism Spectrum Disorderspp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for CrkDefective posttranslational processing activates the tyrosine kinase encoded by the MET proto-oncogene (hepatocyte growth factor receptor).Hepatocyte growth factor/scatter factor-induced intracellular signalling.Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase.Characterization of the novel focal adhesion kinase RAFTK in hematopoietic cells.Invasive growth: from development to metastasisEpigallocatechin-3-gallate inhibits paracrine and autocrine hepatocyte growth factor/scatter factor-induced tumor cell migration and invasion.Receptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) function.Receptor tyrosine kinase signaling: a view from quantitative proteomics.HGF-independent potentiation of EGFR action by c-MetDistinct pathways of genomic progression to benign and malignant tumors of the liver.Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene.Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice.Constitutive activation of the RON gene promotes invasive growth but not transformation.Activating mutations for the met tyrosine kinase receptor in human cancer.HGF/SF and its receptor c-MET play a minor role in the dissemination of human B-lymphoma cells in SCID mice.SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence.Current understanding of the molecular mechanisms of kidney cancer: a primer for urologists.C-terminal truncated forms of Met, the hepatocyte growth factor receptorThe autism-associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrainMET as a target for treatment of chest tumorsBiochemical basis for the functional switch that regulates hepatocyte growth factor receptor tyrosine kinase activationA functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis.Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor.MET pathway as a therapeutic target.Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines.Hepatocyte growth factor is a coupling factor for osteoclasts and osteoblasts in vitro.Targeting the MET oncogene in cancer and metastases.Role of met axis in head and neck cancer.MET receptor tyrosine kinase as an autism genetic risk factor.cMET in triple-negative breast cancer: is it a therapeutic target for this subset of breast cancer patients?Phosphotyrosine profiling of NSCLC cells in response to EGF and HGF reveals network specific mediators of invasion.
P2860
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P2860
The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation
@ast
The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation
@en
type
label
The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation
@ast
The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation
@en
prefLabel
The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation
@ast
The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation
@en
P2093
P2860
P356
P1476
The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation
@en
P2093
Comoglio PM
Ferracini R
P2860
P304
P356
10.1128/MCB.11.4.1793
P407
P577
1991-04-01T00:00:00Z