Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons
about
Genetic manipulation in pigsImmune modulation in xenotransplantationCardiac xenotransplantation: progress and challengesGenetically-engineered pig-to-baboon liver xenotransplantation: histopathology of xenografts and native organsCoagulation dysregulation as a barrier to xenotransplantation in the primateControlling coagulation dysregulation in xenotransplantation.Potential factors influencing the development of thrombocytopenia and consumptive coagulopathy after genetically modified pig liver xenotransplantation.Up to 9-day survival and control of thrombocytopenia following alpha1,3-galactosyl transferase knockout swine liver xenotransplantation in baboonsImmunobiology of liver xenotransplantation.Increased transfusion-free survival following auxiliary pig liver xenotransplantation.Pig-to-baboon heterotopic heart transplantation--exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimens.Further evidence for sustained systemic inflammation in xenograft recipients (SIXR).The Effects of Exogenous Administration of Human Coagulation Factors Following Pig-to-Baboon Liver XenotransplantationCytokine profiles in Tibetan macaques following α-1,3-galactosyltransferase-knockout pig liver xenotransplantation.Rejection of cardiac xenografts transplanted from alpha1,3-galactosyltransferase gene-knockout (GalT-KO) pigs to baboons.Overcoming the barriers to xenotransplantation: prospects for the futureHistopathologic insights into the mechanism of anti-non-Gal antibody-mediated pig cardiac xenograft rejectionReduced binding of human antibodies to cells from GGTA1/CMAH KO pigs.The role of genetically engineered pigs in xenotransplantation research.Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograftThe innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipientsProgress in pig-to-non-human primate transplantation models (1998-2013): a comprehensive review of the literatureB-cell depletion extends the survival of GTKO.hCD46Tg pig heart xenografts in baboons for up to 8 months.Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen.Effect of hyperkalemia and hemolysis caused by hyperacute rejection on cardiac function in pig to human ex vivo xenogeneic cardiac perfusion model.Initial in vivo experience of pig artery patch transplantation in baboons using mutant MHC (CIITA-DN) pigsAlpha 1,3-galactosyltransferase deficiency in pigs increases sialyltransferase activities that potentially raise non-gal xenoantigenicity.Protection of porcine endothelial cells against apoptosis with interleukin-4.Human CD55 expression blocks hyperacute rejection and restricts complement activation in Gal knockout cardiac xenografts.Recent investigations into pig antigen and anti-pig antibody expressionCurrent status of pig heart xenotransplantation.Which anti-platelet therapies might be beneficial in xenotransplantation?Xenotransplantation as a model of integrated, multidisciplinary researchAchieving tolerance in pig-to-primate xenotransplantation: reality or fantasy.Minimal effect of bortezomib in reducing anti-pig antibodies in human leukocyte antigen-sensitized patients: a pilot study.Complement activation and coagulation in xenotransplantation.Rat-to-Chinese tree shrew heart transplantation is a novel small animal model to study non-Gal-mediated discordant xenograft humoral rejection.Immunological challenges and therapies in xenotransplantation.The anti-nonGal xenoantibody response to alpha1,3-galactosyltransferase gene knockout pig xenografts.Gal/non-Gal antigens in pig tissues and human non-Gal antibodies in the GalT-KO era.
P2860
Q24654314-7BEE8C59-75C4-4BFE-AB13-245C84C3F7CAQ26826905-9B963634-9E3C-4B12-94F9-D0CE3B7B3B69Q27024045-17D68ADD-15AC-4A53-AB20-BF47B25A5C93Q28732872-89E1B147-03D9-4D59-9AE2-144EC1BA6884Q33381973-8FC0AD18-0950-45CA-91E7-5D9C430B597AQ33394542-8C4B7862-20D6-4AF1-A7BC-F3BCE066EA40Q33401474-C778FB3D-2C93-4117-B10A-B5466D56D5F0Q33402895-683B44E6-B314-4DDE-ABCD-8ED5F2AC806EQ33403888-32E8ACBB-F861-4223-AD87-06FCA0FBCBA0Q33417115-5C28DC64-BE9C-447D-A015-B79DE2703DCEQ33421736-5C1E586C-360F-4866-84CC-34FB4151DBEEQ33425296-15ACC665-B99C-454F-8B8A-C04E742C6019Q33427920-E2D6CC05-3856-451A-9BD5-1511DC8B4A12Q33443697-1661D6BA-18DC-4544-B72B-B9730332E8ECQ33718060-4F34661A-C417-403F-8181-A4D1F4457E80Q33801035-F6B5BE53-41D1-48D5-81BF-448439B40142Q34018912-BD8C339E-163D-462A-BB09-0D454FBAF5E2Q34041201-747BC24B-9B35-453D-8D23-5845670F7864Q34044894-6F572A2A-04EB-4AAE-A1F0-5E34A091D6F2Q34046578-C952A0F4-5FE3-45BE-A7A2-E187098AF980Q34055520-3B522222-2A7E-45CA-8ADB-FFD3031F359EQ34250530-C61774AE-E467-4045-B5C3-5551721D522DQ34279203-F824BC33-EF37-4758-A4CB-47890954E86DQ34674815-D18AFCA5-02CB-44E1-AD40-A5C5343B6DFFQ34811446-472E3BBE-0938-49A4-AE8B-D581471D87D3Q35202459-A7523D73-D9CC-4225-8DDB-7BBC4405761AQ35496877-C8DF8070-98F0-4826-9936-06EB956A3E13Q35688135-AE09B603-65FA-4A0B-9AC0-C3DC66B86499Q35857059-0791CF01-275F-4DE5-9617-652518D4CA38Q36386185-3290A609-52CE-4F4A-AF54-887140B31D41Q36386394-7CB30B33-D07B-45D7-A6CA-FA10F8B966A1Q37069089-8F6D3C92-383B-4F7F-B9D0-178D91A0F9DBQ37137178-C81C8196-697E-467F-878B-C487FC4F8BF2Q37342291-4E3F4D9A-C5A3-49EB-A3CE-3B79E4AA90EEQ37361071-E7810786-572F-4C79-946E-DEB0041BF187Q37372498-D1E19998-9358-4552-A89A-8B9D797A2FD5Q37600806-7D912892-38A9-48BB-B25A-E9610CA96076Q37670770-534CE068-0290-4715-B01F-C6D45FFD8968Q37675808-704DA76A-5C0A-43D4-9966-EB29219C6174Q37919109-21E9ECE2-406A-4400-B889-76B9B774C6C6
P2860
Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Thrombotic microangiopathy ass ...... gene-knockout pigs in baboons
@ast
Thrombotic microangiopathy ass ...... gene-knockout pigs in baboons
@en
type
label
Thrombotic microangiopathy ass ...... gene-knockout pigs in baboons
@ast
Thrombotic microangiopathy ass ...... gene-knockout pigs in baboons
@en
prefLabel
Thrombotic microangiopathy ass ...... gene-knockout pigs in baboons
@ast
Thrombotic microangiopathy ass ...... gene-knockout pigs in baboons
@en
P2093
P2860
P1476
Thrombotic microangiopathy ass ...... gene-knockout pigs in baboons
@en
P2093
Akira Shimizu
David H Sachs
David K C Cooper
Frank J M F Dor
Henk-Jan Schuurman
Kazuhiko Yamada
Kenji Kuwaki
Robert B Colvin
Simon C Robson
Stuart L Houser
P2860
P304
P356
10.2353/AJPATH.2008.070672
P407
P577
2008-05-08T00:00:00Z