Human CD55 expression blocks hyperacute rejection and restricts complement activation in Gal knockout cardiac xenografts.
about
Kidney xenotransplantationImmunobiological barriers to xenotransplantationImmunological and physiological observations in baboons with life-supporting genetically engineered pig kidney grafts.Anti-non-Gal-specific combination treatment with an anti-idiotypic Ab and an inhibitory small molecule mitigates the xenoantibody response.Histopathologic insights into the mechanism of anti-non-Gal antibody-mediated pig cardiac xenograft rejectionRhesus monkeys and baboons develop clotting factor VIII inhibitors in response to porcine endothelial cells or islets.The role of genetically engineered pigs in xenotransplantation research.Double transgenic pigs with combined expression of human α1,2-fucosyltransferase and α-galactosidase designed to avoid hyperacute xenograft rejectionProgress in pig-to-non-human primate transplantation models (1998-2013): a comprehensive review of the literatureControl of IBMIR in neonatal porcine islet xenotransplantation in baboonsDevelopment of a consensus protocol to quantify primate anti-non-Gal xenoreactive antibodies using pig aortic endothelial cellsCloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen.Bortezomib, C1-inhibitor and plasma exchange do not prolong the survival of multi-transgenic GalT-KO pig kidney xenografts in baboonsXenoantibody response to porcine islet cell transplantation using GTKO, CD55, CD59, and fucosyltransferase multiple transgenic donorsRecent investigations into pig antigen and anti-pig antibody expressionCurrent status of pig heart xenotransplantation.Initial in vitro studies on tissues and cells from GTKO/CD46/NeuGcKO pigs.Efficient production of multi-modified pigs for xenotransplantation by 'combineering', gene stacking and gene editing.Minimal effect of bortezomib in reducing anti-pig antibodies in human leukocyte antigen-sensitized patients: a pilot study.Early graft failure of GalTKO pig organs in baboons is reduced by expression of a human complement pathway-regulatory protein.The role of complement in the early immune response to transplantation.Xenotransplantation literature update, March to April 2012.New concepts of immune modulation in xenotransplantation.Xenotransplantation: immunological hurdles and progress toward tolerance.The pathobiology of pig-to-primate xenotransplantation: a historical review.Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: an alternative to direct complement regulation.Recent advances in understanding xenotransplantation: implications for the clinic.First quantification of alpha-Gal epitope in current glutaraldehyde-fixed heart valve bioprosthesis (by Naso et al.).Porcine to Human Heart Transplantation: Is Clinical Application Now Appropriate?Encouraging experience using multi-transgenic xenografts in a pig-to-baboon cardiac xenotransplantation model.Effect of TNF-alpha blockade on coagulopathy and endothelial cell activation in xenoperfused porcine kidneys.Low anti-pig antibody levels are key to the success of solid organ xenotransplantation: But is this sufficient?
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P2860
Human CD55 expression blocks hyperacute rejection and restricts complement activation in Gal knockout cardiac xenografts.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Human CD55 expression blocks h ...... l knockout cardiac xenografts.
@ast
Human CD55 expression blocks h ...... l knockout cardiac xenografts.
@en
type
label
Human CD55 expression blocks h ...... l knockout cardiac xenografts.
@ast
Human CD55 expression blocks h ...... l knockout cardiac xenografts.
@en
prefLabel
Human CD55 expression blocks h ...... l knockout cardiac xenografts.
@ast
Human CD55 expression blocks h ...... l knockout cardiac xenografts.
@en
P2093
P2860
P1433
P1476
Human CD55 expression blocks h ...... l knockout cardiac xenografts.
@en
P2093
Christopher G A McGregor
Davide Ricci
Elise A Oehler
Guerard W Byrne
Henry D Tazelaar
Naoto Miyagi
Paul G Stalboerger
P2860
P304
P356
10.1097/TP.0B013E3182472850
P577
2012-04-01T00:00:00Z