Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoter
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Developmental silencing of human zeta-globin gene expression is mediated by the transcriptional repressor RREB1A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteinsZinc fingers 1-7 of EVI1 fail to bind to the GATA motif by itself but require the core site GACAAGATA for bindingRescue of erythroid development in gene targeted GATA-1- mouse embryonic stem cellsThe effect of chromatin structure on cisplatin damage in intact human cells.Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences.Structural and functional cross-talk between a distant enhancer and the epsilon-globin gene promoter shows interdependence of the two elements in chromatin.The two zinc finger-like domains of GATA-1 have different DNA binding specificitiesOverexpression of human GATA-1 and GATA-2 interferes with spine formation and produces depressive behavior in rats.Mutation of gene-proximal regulatory elements disrupts human epsilon-, gamma-, and beta-globin expression in yeast artificial chromosome transgenic micePhylogenetic footprinting reveals unexpected complexity in trans factor binding upstream from the epsilon-globin gene.Essential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5' hypersensitive site 2 of the beta-globin locus control regionEnhancer-dependent transcription of the epsilon-globin promoter requires promoter-bound GATA-1 and enhancer-bound AP-1/NF-E2Transcriptional activation of human zeta 2 globin promoter by the alpha globin regulatory element (HS-40): functional role of specific nuclear factor-DNA complexes.Developmental regulation of the human embryonic beta-like globin gene is mediated by synergistic interactions among multiple tissue- and stage-specific elementsPrimary sequence and epigenetic determinants of in vivo occupancy of genomic DNA by GATA1.GATA1 and YY1 are developmental repressors of the human epsilon-globin gene.Transcriptional activation of human leukosialin (CD43) gene by Sp1 through binding to a GGGTGG motif.In vivo footprinting analysis of the hepatic control region of the human apolipoprotein E/C-I/C-IV/C-II gene locus.Regulator of G protein signaling 4 is a novel target of GATA-6 transcription factor.Transcriptional and post-transcriptional regulation of Sprouty1, a receptor tyrosine kinase inhibitor in prostate cancer.In vitro and in vivo protein--DNA interactions on the rat erythroid-specific L' pyruvate kinase gene promoter.A (GATA)(7) motif located in the 5' boundary area of the human beta-globin locus control region exhibits silencer activity in erythroid cells.Developmental control of epsilon- and gamma-globin genes.Multiple epsilon-promoter elements participate in the developmental control of epsilon-globin genes in transgenic mice.Developmental effect of the XmnI site on Ggamma-globin gene expression among newborn Hb F-Malta-I [Ggamma117(G19)His-->Arg, CAT-->CGT] heterozygotes and adult beta+ -Thalassemia homozygotes.Differential binding of the NFE3 and CP1/NFY transcription factors to the human gamma- and epsilon-globin CCAAT boxes.
P2860
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P2860
Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoter
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoter
@ast
Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoter
@en
type
label
Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoter
@ast
Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoter
@en
prefLabel
Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoter
@ast
Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoter
@en
P2093
P2860
P356
P1476
Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoter
@en
P2093
P2860
P304
P356
10.1128/MCB.11.5.2558
P407
P577
1991-05-01T00:00:00Z