Global brain delivery of neprilysin gene by intravascular administration of AAV vector in mice.
about
Biology of adeno-associated viral vectors in the central nervous systemTargeting heat shock proteins to modulate α-synuclein toxicityIL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline.Systemic gene delivery to the central nervous system using Adeno-associated virus.Catalytic immunoglobulin gene delivery in a mouse model of Alzheimer's disease: prophylactic and therapeutic applications.New therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy.HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice.Granulocyte-colony stimulating factor attenuates oligomeric amyloid β neurotoxicity by activation of neprilysin.Mutations in MME cause an autosomal-recessive Charcot-Marie-Tooth disease type 2.Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer's DiseaseTailored transgene expression to specific cell types in the central nervous system after peripheral injection with AAV9.Metabolism of amyloid β peptide and pathogenesis of Alzheimer's disease.Amyloid-clearing proteins and their epigenetic regulation as a therapeutic target in Alzheimer's disease.Gene therapy for neurological disorders.New Insights into Epigenetic and Pharmacological Regulation of Amyloid-Degrading Enzymes.Aβ-Degrading Proteases: Therapeutic Potential in Alzheimer Disease.Activation of 5-HT(2C) receptor promotes the expression of neprilysin in U251 human glioma cells.Gene therapy for a mouse model of glucose transporter-1 deficiency syndrome.Transduction Profile of the Marmoset Central Nervous System Using Adeno-Associated Virus Serotype 9 Vectors.The role of amyloid beta clearance in cerebral amyloid angiopathy: more potential therapeutic targets.Aβ degradation-the inside story.Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons.Dysregulated Metabolism of the Amyloid-β Protein and Therapeutic Approaches in Alzheimer Disease.The relationship between cholesterol level and Alzheimer's disease-associated APP proteolysis/Aβ metabolism.Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease.Innate immune activation in Alzheimer’s disease.
P2860
Q21129328-C898C18B-E866-4BDB-A6BC-BF2CD216122BQ26827066-31CE2200-4AA7-4BE0-8F6B-BDC16984EF80Q27315329-FD992BA7-C040-4B60-9514-C5F838297807Q33695674-428A8573-02AF-44D6-A71B-4B07F095CAFCQ34345602-F4C4F0F8-9378-4B36-8572-B5F315795CA1Q34368970-177A14FE-0EC3-4A17-ACA2-434BACE99DD3Q35023867-C0E35940-E2F8-41B7-9552-41D904D25782Q35213148-E4B3581B-A6B8-4AAB-A901-24F9126C1ECFQ37348968-EA86532C-F6F9-42C9-8BA6-473CF8CD9091Q37408544-BFFD1AD5-AF83-43AE-A9D8-65EF09CBF831Q37481531-2E445953-7F9B-4B7A-9290-B83184CDB5FCQ38123911-66F8FACF-C04F-46AC-95B9-DBD8108992A1Q38256360-F67B3A99-5A2E-46BB-8362-841D6BFEB857Q38661071-0A967B74-F509-4325-8FA6-EF4FC93C44D7Q38834930-3F94F448-54B1-4645-91EB-70D6DD81A5A8Q38878922-363D2334-948B-42E6-8986-8D3C7B9035E6Q38934489-A308BD08-3A0B-4CC2-BE83-D8069A9C332CQ40365796-C7B81220-764C-4D4A-B767-E89EA256E379Q40906363-652E5DE0-32B8-41EC-80B7-2CCC4E7BA7E5Q41439008-5984E97E-5B63-4ECE-8BDB-FD56CB903922Q41873573-F853FD16-1EA1-42D0-87C4-12DC4DB69B21Q42263324-C209CD50-553C-4BEF-8686-6132731CAFD8Q48165579-48B90176-72C4-4FC5-AF32-83C3CF0CE29DQ50082084-E17BFC9A-3445-4902-9DB9-FB8A608E3694Q53397508-199BB396-6F99-4E2C-8E50-84A4C22DB27BQ55289589-3EC4CB3A-5529-40A0-99EA-BCE64AC886BE
P2860
Global brain delivery of neprilysin gene by intravascular administration of AAV vector in mice.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Global brain delivery of nepri ...... tration of AAV vector in mice.
@ast
Global brain delivery of nepri ...... tration of AAV vector in mice.
@en
type
label
Global brain delivery of nepri ...... tration of AAV vector in mice.
@ast
Global brain delivery of nepri ...... tration of AAV vector in mice.
@en
prefLabel
Global brain delivery of nepri ...... tration of AAV vector in mice.
@ast
Global brain delivery of nepri ...... tration of AAV vector in mice.
@en
P2093
P2860
P356
P1433
P1476
Global brain delivery of nepri ...... tration of AAV vector in mice.
@en
P2093
Akane Takahashi
Makoto Higuchi
Masashi Asai
Misaki Sekiguchi
Nobuhisa Iwata
Shin-ichi Muramatsu
Takaomi C Saido
Yoshino Hattori
P2860
P2888
P356
10.1038/SREP01472
P407
P577
2013-01-01T00:00:00Z