Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome. - Wikidata - awgldk - TriplyDB

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome.

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome.

http://www.wikidata.org/entity/Q36693574

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The sequence of human chromosome 21 and implications for research into Down syndrome DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase Down syndrome: searching for the genetic culprits Prospects for Improving Brain Function in Individuals with Down Syndrome Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter Dissecting Alzheimer disease in Down syndrome using mouse models Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities Neurological phenotypes for Down syndrome across the life span Effects of neonatal neural progenitor cell implantation on adult neuroanatomy and cognition in the Ts65Dn model of Down syndrome Principal Component Analysis of the Effects of Environmental Enrichment and (-)-epigallocatechin-3-gallate on Age-Associated Learning Deficits in a Mouse Model of Down Syndrome Animal models of intellectual disability: towards a translational approach Pre- and postnatal exposure to low dose glufosinate ammonium induces autism-like phenotypes in mice.Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome Digastric Muscle Phenotypes of the Ts65Dn Mouse Model of Down Syndrome Synaptojanin-1 plays a key role in astrogliogenesis: possible relevance for Down's syndrome Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer.The use of mouse models to understand and improve cognitive deficits in Down syndrome.Brain plasticity and disease: a matter of inhibition.Behavioral validation of the Ts65Dn mouse model for Down syndrome of a genetic background free of the retinal degeneration mutation Pde6b(rd1).Live imaging of neuronal connections by magnetic resonance: Robust transport in the hippocampal-septal memory circuit in a mouse model of Down syndrome.Ultrasonic vocalizations: a tool for behavioural phenotyping of mouse models of neurodevelopmental disorders.Advanced microscopic imaging methods to investigate cortical development and the etiology of mental retardation.The mouse brain transcriptome by SAGE: differences in gene expression between P30 brains of the partial trisomy 16 mouse model of Down syndrome (Ts65Dn) and normals Transgenic mouse in vivo library of human Down syndrome critical region 1: association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration.Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice.Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model.Molecular basis of pharmacotherapies for cognition in Down syndrome Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome.Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition.Synthesis and in vitro biological evaluation of carbonyl group-containing inhibitors of vesicular acetylcholine transporter Segmental trisomy of chromosome 17: a mouse model of human aneuploidy syndromes Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion.Gene expression levels assessed by CA1 pyramidal neuron and regional hippocampal dissections in Alzheimer's disease Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice.Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome.Perinatal choline supplementation improves cognitive functioning and emotion regulation in the Ts65Dn mouse model of Down syndrome Abnormal microRNA expression in Ts65Dn hippocampus and whole blood: contributions to Down syndrome phenotypes.Defective cerebellar response to mitogenic Hedgehog signaling in Down [corrected] syndrome mice.

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Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome.

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

The trk family of tyrosine protein kinase receptors

Developments of a water-maze procedure for studying spatial learning in the rat

Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes

Dysregulation of gene expression in mouse trisomy 16, an animal model of Down syndrome.

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.

Evolutionary conservation of the mouse apolipoprotein e-c1-c2 gene cluster: structure and genetic variability in inbred mice.

Cell loss and shrinkage in the nucleus basalis Meynert complex in Alzheimer's disease.

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