Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice
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The role of metallothionein in the pathogenesis of acute lung injuryLocus control regionsA murine model of Menkes disease reveals a physiological function of metallothioneinThe fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 elementZinc deficiency primes the lung for ventilator-induced injuryNK1, a natural splice variant of hepatocyte growth factor/scatter factor, is a partial agonist in vivoDisassociation of met-mediated biological responses in vivo: the natural hepatocyte growth factor/scatter factor splice variant NK2 antagonizes growth but facilitates metastasis.Expression of a dominant-negative mutant TGF-beta type II receptor in transgenic mice reveals essential roles for TGF-beta in regulation of growth and differentiation in the exocrine pancreas.Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning.Dividing the empire: boundary chromatin elements delimit the territory of enhancers.Human matrix attachment regions insulate transgene expression from chromosomal position effects in Drosophila melanogaster.Rat growth hormone gene introns stimulate nucleosome alignment in vitro and in transgenic miceExpression of mutant human cystathionine beta-synthase rescues neonatal lethality but not homocystinuria in a mouse model.GIP-overexpressing mice demonstrate reduced diet-induced obesity and steatosis, and improved glucose homeostasisIn vivo disruption of TGF-beta signaling by Smad7 leads to premalignant ductal lesions in the pancreasMouse models of breast cancer metastasis.The transcription factors MTF-1 and USF1 cooperate to regulate mouse metallothionein-I expression in response to the essential metal zinc in visceral endoderm cells during early developmentAnalysis of the effects of overexpression of metallothionein-I in transgenic mice on the reproductive toxicology of cadmiumThe 5' flanking region of the rat LAP (C/EBP beta) gene can direct high-level, position-independent, copy number-dependent expression in multiple tissues in transgenic mice.Targeted disruption of metallothionein I and II genes increases sensitivity to cadmiumStability of protein production from recombinant mammalian cells.Genetically engineered mice as experimental tools to dissect the critical events in breast cancerAntiapoptotic effect and inhibition of ischemia/reperfusion-induced myocardial injury in metallothionein-overexpressing transgenic mice.The beta-globin locus control region enhances transcription of but does not confer position-independent expression onto the lacZ gene in transgenic mice.Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factorTransgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injuryOverexpression of NK2 inhibits liver regeneration after partial hepatectomy in mice.Neural regulation of muscle acetylcholine receptor epsilon- and alpha-subunit gene promoters in transgenic miceEvidence for a protective role of metallothionein-1 in focal cerebral ischemiaA globin enhancer acts by increasing the proportion of erythrocytes expressing a linked transgene.A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes.Scaffold attachment regions stimulate HSP70.1 expression in mouse preimplantation embryos but not in differentiated tissuesFast-muscle-specific expression of human aldolase A transgenesThe effect of dietary modulation of sulfur amino acids on cystathionine β synthase-deficient mice.The mutationally activated Met receptor mediates motility and metastasis.Modeling metastatic breast cancer in mice.Cystathionine beta-synthase p.S466L mutation causes hyperhomocysteinemia in mice.Dysfunctional transforming growth factor-beta receptor II accelerates prostate tumorigenesis in the TRAMP mouse modelContrasting effects of the SATB1 core nuclear matrix attachment region and flanking sequences of the keratin 18 gene in transgenic miceScatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development.
P2860
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P2860
Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Distal regulatory elements fro ...... expression in transgenic mice
@ast
Distal regulatory elements fro ...... expression in transgenic mice
@en
type
label
Distal regulatory elements fro ...... expression in transgenic mice
@ast
Distal regulatory elements fro ...... expression in transgenic mice
@en
prefLabel
Distal regulatory elements fro ...... expression in transgenic mice
@ast
Distal regulatory elements fro ...... expression in transgenic mice
@en
P2093
P2860
P356
P1476
Distal regulatory elements fro ...... expression in transgenic mice
@en
P2093
D M Koeller
E P Sandgren
R D Palmiter
R L Brinster
P2860
P304
P356
10.1128/MCB.13.9.5266
P407
P577
1993-09-01T00:00:00Z