Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors. - Wikidata - awgldk - TriplyDB

Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors.

Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors.

http://www.wikidata.org/entity/Q36698501

about

Stem cell technology in breast cancer: current status and potential applications Notch signaling deregulation in multiple myeloma: A rational molecular target γ-Secretase inhibitors and modulators.Identifying and targeting tumor-initiating cells in the treatment of breast cancer Targeting the Notch signaling pathway in cancer therapeutics Brain tumor stem cells: Molecular characteristics and their impact on therapy Can nanomedicines kill cancer stem cells?Cancer Stem and Progenitor-Like Cells as Pharmacological Targets in Breast Cancer Treatment Patient-derived xenograft models of breast cancer and their predictive power Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer.Notch signalling pathway as an oncogenic factor involved in cancer development Chemotherapy induces Notch1-dependent MRP1 up-regulation, inhibition of which sensitizes breast cancer cells to chemotherapy.RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation Chloroquine eliminates cancer stem cells through deregulation of Jak2 and DNMT1.Notch signaling in serous ovarian cancer.Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application.The colon: from banal to brilliant.NOTCH pathway inactivation promotes bladder cancer progression Transient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulation Nontranscriptional role of Hif-1α in activation of γ-secretase and notch signaling in breast cancer.Notch signaling activation in pediatric low-grade astrocytoma Inhibition of iNOS as a novel effective targeted therapy against triple-negative breast cancer.Cripto-1 as a novel therapeutic target for triple negative breast cancer.Notch reporter activity in breast cancer cell lines identifies a subset of cells with stem cell activity.Targeted therapy against cancer stem cells.Therapeutic Implications of Cellular Heterogeneity and Plasticity in Breast Cancer Aberrant activation of Notch signaling in extrahepatic cholangiocarcinoma: clinicopathological features and therapeutic potential for cancer stem cell-like properties Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study.Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo.Emerging therapeutic targets in metastatic progression: A focus on breast cancer.Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer.The autophagy inhibitor chloroquine targets cancer stem cells in triple negative breast cancer by inducing mitochondrial damage and impairing DNA break repair.Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses.Vasculogenic mimicry in small cell lung cancer.Hypoxia, notch signalling, and prostate cancer.Targeting notch signaling pathway in cancer: clinical development advances and challenges Cancer stem cells and their implication in breast cancer.Molecular pathways: translational and therapeutic implications of the Notch signaling pathway in cancer Cancer stem cells: are they responsible for treatment failure?

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P2860

Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors.

http://www.wikidata.org/entity/Q36698501

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Preclinical and clinical studi ...... etaxel on human breast tumors.

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Preclinical and clinical studi ...... etaxel on human breast tumors.

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Preclinical and clinical studi ...... etaxel on human breast tumors.

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Preclinical and clinical studi ...... etaxel on human breast tumors.

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Clinical Cancer Research

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Preclinical and clinical studi ...... etaxel on human breast tumors.

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Amber M Froehlich

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Anne F Schott

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Daniel F Hayes

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P2860

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

Prospective identification of tumorigenic breast cancer cells

Notch signaling: cell fate control and signal integration in development

Notch signaling: from the outside in

Wnt signalling in stem cells and cancer

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

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