Hematopoietic cell fate and the initiation of leukemic properties in primitive primary human cells are influenced by Ras activity and farnesyltransferase inhibition

Hematopoietic cell fate and the initiation of leukemic properties in primitive primary human cells are influenced by Ras activity and farnesyltransferase inhibition

Item
http://www.wikidata.org/entity/Q36701461
Mammary stem cells, self-renewal pathways, and carcinogenesisRal is both necessary and sufficient for the inhibition of myeloid differentiation mediated by RasBypass of senescence, immortalization, and transformation of human hematopoietic progenitor cells.Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells.Pleiotrophin mediates hematopoietic regeneration via activation of RAS.A MEK inhibitor abrogates myeloproliferative disease in Kras mutant mice.Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells.RAS oncogene suppression induces apoptosis followed by more differentiated and less myelosuppressive disease upon relapse of acute myeloid leukemia.Increased c-Jun expression and reduced GATA2 expression promote aberrant monocytic differentiation induced by activating PTPN11 mutantsFrom top to bottom: midkine and pleiotrophin as emerging players in immune regulation.Lonafarnib reduces the resistance of primitive quiescent CML cells to imatinib mesylate in vitro.Eicosapentaenoic acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells.Autologous serum improves yield and metabolic capacity of monocyte-derived hepatocyte-like cells: possible implication for cell transplantation.Wild-type Kras expands and exhausts hematopoietic stem cells.
P2860

Hematopoietic cell fate and the initiation of leukemic properties in primitive primary human cells are influenced by Ras activity and farnesyltransferase inhibition

Item
http://www.wikidata.org/entity/Q36701461
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Hematopoietic cell fate and th ...... farnesyltransferase inhibition
@ast
Hematopoietic cell fate and th ...... farnesyltransferase inhibition
@en
type
label
Hematopoietic cell fate and th ...... farnesyltransferase inhibition
@ast
Hematopoietic cell fate and th ...... farnesyltransferase inhibition
@en
prefLabel
Hematopoietic cell fate and th ...... farnesyltransferase inhibition
@ast
Hematopoietic cell fate and th ...... farnesyltransferase inhibition
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Hematopoietic cell fate and th ...... farnesyltransferase inhibition
@en
P2093
P2860
P304
P31
P356
10.1128/MCB.24.16.6993-7002.2004
P407
P433
P478
P50
P577
P698
P921
P932