Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding.
about
Inactivation of p53 rescues the maintenance of high risk HPV DNA genomes deficient in expression of E6Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins.p53 is regulated by the lysine demethylase LSD1The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2Modulation of the vitamin D3 response by cancer-associated mutant p53Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activationDirect involvement of p53 in programmed cell death of oligodendrocytesRepression of SHP-1 expression by p53 leads to trkA tyrosine phosphorylation and suppression of breast cancer cell proliferationSIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasisInhibition of p53 DNA binding by human papillomavirus E6 proteinsNovel mutants of NAB corepressors enhance activation by Egr transactivatorsThe p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathwayEpigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cellsHistone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosisThe Contrived Mutant p53 Oncogene - Beyond Loss of FunctionsAcquisition order of Ras and p53 gene alterations defines distinct adrenocortical tumor phenotypesConformational stability and activity of p73 require a second helix in the tetramerization domainSolution structure of the tetrameric minimum transforming domain of p53Refined solution structure of the oligomerization domain of the tumour suppressor p53Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstromsDeath-associated protein 4 binds MST1 and augments MST1-induced apoptosisIntegrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosisInactivation of wild-type p53 by a dominant negative mutant renders MCF-7 cells resistant to tubulin-binding agent cytotoxicityBax and Bak independently promote cytochrome C release from mitochondriaRequirement of 3-phosphoinositide-dependent protein kinase-1 for BDNF-mediated neuronal survivalRNA polymerase 1-driven transcription as a mediator of BDNF-induced neurite outgrowthFeedback control of p53 translation by REDD1 and mTORC1 limits the p53-dependent DNA damage responseThe rate of spontaneous mutations in human myeloid cellsLinking the p53 tumour suppressor pathway to somatic cell reprogrammingMolecular requirements for transformation of fallopian tube epithelial cells into serous carcinoma.Drug resistance associated with loss of p53 involves extensive alterations in microtubule composition and dynamics.Human papillomavirus E6 regulates the cytoskeleton dynamics of keratinocytes through targeted degradation of p53Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapyIdentification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo.Analysis of a protein-binding domain of p53p53 regulates metanephric developmentThe E7 oncoprotein of human papillomavirus type 16 stabilizes p53 through a mechanism independent of p19(ARF).Nuclear factor of activated T-cells isoform c4 (NFATc4/NFAT3) as a mediator of antiapoptotic transcription in NMDA receptor-stimulated cortical neuronsInteractions of the p53 protein family in cellular stress response in gastrointestinal tumorsA mouse mammary epithelial cell model to identify molecular mechanisms regulating breast cancer progression.
P2860
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P2860
Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Identification of a minimal tr ...... sequence-specific DNA binding.
@ast
Identification of a minimal tr ...... sequence-specific DNA binding.
@en
type
label
Identification of a minimal tr ...... sequence-specific DNA binding.
@ast
Identification of a minimal tr ...... sequence-specific DNA binding.
@en
prefLabel
Identification of a minimal tr ...... sequence-specific DNA binding.
@ast
Identification of a minimal tr ...... sequence-specific DNA binding.
@en
P2093
P2860
P356
P1476
Identification of a minimal tr ...... sequence-specific DNA binding.
@en
P2093
P2860
P304
P356
10.1128/MCB.12.12.5581
P407
P577
1992-12-01T00:00:00Z