Nuclear receptor-mediated transcriptional regulation in Phase I, II, and III xenobiotic metabolizing systems.
about
Three-dimensional Huh7 cell culture system for the study of Hepatitis C virus infectionNRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesisPhase I to II cross-induction of xenobiotic metabolizing enzymes: a feedforward control mechanism for potential hormetic responsesEmerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotectionLack of the matricellular protein SPARC (secreted protein, acidic and rich in cysteine) attenuates liver fibrogenesis in miceTranscriptional profiling in C. elegans suggests DNA damage dependent apoptosis as an ancient function of the p53 family.Hepatic xenobiotic metabolizing enzyme and transporter gene expression through the life stages of the mouse.A mechanistic insight into 3,4-methylenedioxymethamphetamine ("ecstasy")-mediated hepatotoxicity.Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease.A novel in vitro pancreatic carcinogenesis model.SNP (-617C>A) in ARE-like loci of the NRF2 gene: a new biomarker for prognosis of lung adenocarcinoma in Japanese non-smoking women.Integrative Network-based Analysis of Colonic Detoxification Gene Expression in Ulcerative Colitis According to Smoking Status.Prediction of drug-induced intrahepatic cholestasis: in vitro screening and QSAR analysis of drugs inhibiting the human bile salt export pump.Nuclear receptors as therapeutic targets in cholestatic liver diseases.Current industrial practices in assessing CYP450 enzyme induction: preclinical and clinicalNrf2 plays an important role in coordinated regulation of Phase II drug metabolism enzymes and Phase III drug transporters.Mind the gut: Dietary impact on germline stem cells and fertility.Regulation of endobiotics glucuronidation by ligand-activated transcription factors: physiological function and therapeutic potential.Nonviral gene transfer as a tool for studying transcription regulation of xenobiotic metabolizing enzymes.Mechanisms of genetic regulation in gene expression: examples from drug metabolizing enzymes and transporters.Hydrodynamic gene delivery and its applications in pharmaceutical research.Toward a new age of cellular pharmacokinetics in drug discovery.Nuclear receptors and endobiotics glucuronidation: the good, the bad, and the UGT.Light- and clock-control of genes involved in detoxification.Phenotypic regulation of liver cells in a biofunctionalized three-dimensional hydrogel platform.Baicalein Decreases Hydrogen Peroxide-Induced Damage to NG108-15 Cells via Upregulation of Nrf2.Establishment of a stable aryl hydrocarbon receptor-responsive HepG2 cell lineCellular impact of combinations of endosulfan, atrazine, and chlorpyrifos on human primary hepatocytes and HepaRG cells after short and chronic exposures.Non-alcoholic fatty liver disease (NAFLD) - pathogenesis, classification, and effect on drug metabolizing enzymes and transporters.Cytogenetic evaluation and the association with polymorphisms of the CPY1A1 and NR1I3 genes in individuals exposed to BTEX.Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury.Constitutive expression of drug metabolizing enzymes and related transcription factors in cattle testis and their modulation by illicit steroids.Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals.Circadian expression profiles of drug-processing genes and transcription factors in mouse liver.PXR ligand classification model with SFED-weighted WHIM and CoMMA descriptors.Curcumin and its derivatives inhibit 2,3,7,8,-tetrachloro-dibenzo-p-dioxin-induced expression of drug metabolizing enzymes through aryl hydrocarbon receptor-mediated pathway.Transcription factor aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator is involved in regulation of the xenobiotic tolerance-related cytochrome P450 CYP6DA2 in Aphis gossypii Glover.Sulforaphane Regulates NFE2L2/Nrf2-Dependent Xenobiotic Metabolism Phase II and Phase III Enzymes Differently in Human Colorectal Cancer and Untransformed Epithelial Colon Cells.Effects of phenol on metabolic activities and transcription profiles of cytochrome P450 enzymes in Chironomus kiinensis larvae.Ursodeoxycholate Restores Biliary Excretion of Methotrexate in Rats with Ethinyl Estradiol Induced-Cholestasis by Restoring Canalicular Mrp2 Expression.
P2860
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P2860
Nuclear receptor-mediated transcriptional regulation in Phase I, II, and III xenobiotic metabolizing systems.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Nuclear receptor-mediated tran ...... nobiotic metabolizing systems.
@ast
Nuclear receptor-mediated tran ...... nobiotic metabolizing systems.
@en
type
label
Nuclear receptor-mediated tran ...... nobiotic metabolizing systems.
@ast
Nuclear receptor-mediated tran ...... nobiotic metabolizing systems.
@en
prefLabel
Nuclear receptor-mediated tran ...... nobiotic metabolizing systems.
@ast
Nuclear receptor-mediated tran ...... nobiotic metabolizing systems.
@en
P2093
P356
P1476
Nuclear receptor-mediated tran ...... nobiotic metabolizing systems.
@en
P2093
Hiroshi Tanaka
Kotoko Nakata
Tatsuhiko Adachi
Tatsuya Nakano
Toshihisa Ishikawa
Tsuguchika Kaminuma
Yoshitomo Tanaka
P304
P356
10.2133/DMPK.21.437
P577
2006-12-01T00:00:00Z