about
A genome-wide association study identifies five loci influencing facial morphology in EuropeansNIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycleExome sequence identifies RIPK4 as the Bartsocas-Papas syndrome locusMicroRNA 203 expression in keratinocytes is dependent on regulation of p53 levels by E6DeltaNp63 knockdown mice: A mouse model for AEC syndromeTargeting of Mutant p53 and the Cellular Redox Balance by APR-246 as a Strategy for Efficient Cancer TherapyModeling AEC-New approaches to study rare genetic disordersStructures of p63 DNA binding domain in complexes with half-site and with spacer-containing full response elementsStructural basis of p63α SAM domain mutants involved in AEC syndromePliable DNA Conformation of Response Elements Bound to Transcription Factor p63Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence codeMechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerizationA step closer toward therapies for p63-related disordersA genetic variants database for arrhythmogenic right ventricular dysplasia/cardiomyopathySpectrum of p63 mutations in a selected patient cohort affected with ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (AEC)APR-246/PRIMA-1(MET) rescues epidermal differentiation in skin keratinocytes derived from EEC syndrome patients with p63 mutationsDefective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant miceThe retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic developmentDiscovering biological connections between experimental conditions based on common patterns of differential gene expressionTranscriptional network of p63 in human keratinocytes.Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.Variation at genes influencing facial morphology are not associated with developmental imprecision in human faces.{Delta}Np73{beta} puts the brakes on DNA repair.p53/p63/p73 in the epidermis in health and diseaseIntegrating animal models and in vitro tissue models to elucidate the role of desmosomal proteins in diseases.The human papillomavirus E6 oncogene represses a cell adhesion pathway and disrupts focal adhesion through degradation of TAp63β upon transformationp63 in skin development and ectodermal dysplasias.p63 and p73, the ancestors of p53.Tracing the protectors path from the germ line to the genome.TAp63 is important for cardiac differentiation of embryonic stem cells and heart development.Heritability of craniofacial structures in normal subjects and patients with sleep apnea.Analysis of large phenotypic variability of EEC and SHFM4 syndromes caused by K193E mutation of the TP63 gene.p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasisInteraction between IRF6 and TGFA genes contribute to the risk of nonsyndromic cleft lip/palateSusceptibility to DNA damage as a molecular mechanism for non-syndromic cleft lip and palate.p63 maintains keratinocyte proliferative capacity through regulation of Skp2-p130 levels.The carboxy-terminus of p63 links cell cycle control and the proliferative potential of epidermal progenitor cells.A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis.
P2860
Q21563366-13DED763-3B63-42DF-9F98-C68677D960DFQ24298090-94A1CB64-29EC-407E-8C17-C0B672A862DEQ24300588-A2380DE8-9AAE-4CDA-A643-08149E6B284EQ24594575-80138BFC-B0C9-4A21-8987-F8A854205D04Q24645471-30803CD4-0AE6-470A-857A-55568B5F4D97Q26766341-D642C331-CA27-4C33-91B9-5BD7E72C98B7Q26996543-36009B10-7E02-4B3D-93F9-1C590B2EC02FQ27667425-B2B670BC-715F-466E-93BD-27C20E45E4E9Q27668032-9B34F16A-C49A-4474-8510-249EE5B070B2Q27676758-66DF7CB4-20FB-4C39-A4D9-EB70B61E0F70Q27679224-808236B2-FF2B-4EB1-A67E-5368CB2482C4Q27728187-2D4BFBC9-CD6B-4351-8597-C21267D31065Q28243496-34A45DA0-3BCA-44D9-B2D4-29C13BAD5583Q28250468-F63A3CBB-BDFD-4063-98CA-8799F5CDC9C0Q28254802-280DFE64-57DC-4A5C-B15E-D12976520066Q28284341-0542D464-0393-4E5B-909C-E1EA98CCF67BQ28586893-059DF076-CE54-4AB5-B010-7EAC6CCBB2EBQ28590539-A511C2AA-2E70-40CA-93D2-AD5586FAEB87Q28593890-ABD3233F-9D6B-4DC4-BC38-DDC7CFDCC92AQ28743395-4A2DB66A-E96D-4D27-B3E1-110BE0ABB354Q33434504-6498AC99-2CE6-446C-AD1D-38CFFEA02F7BQ33680682-E62B38ED-F594-4E75-9D06-9B85E1EA88E0Q33688548-47E27D8F-8220-4B34-A873-8AB4EE4D90C4Q33734134-22C6077A-DA4F-4A3D-AD8D-03AB75F69E7BQ33737785-12546412-1056-4496-9B0E-E88FB4344867Q33944382-A407AA9D-CBFD-4883-ADA2-8ABE6664D0C5Q33980398-0827378A-EC38-49AA-AE86-9B97A6989E08Q34042655-2D5432E3-2CE3-4A0A-BF35-451370C1EE47Q34058121-56E03195-8E3A-4948-9021-100764824FF4Q34080237-9998B800-2A57-4744-AD16-20D322402EEDQ34100529-3849CAB7-8A07-44C8-BAEA-3BC03C5A20C6Q34214162-75847581-10B6-4686-8F7E-8115BB620765Q34238348-79174D42-23B9-4404-9F57-A718D7E880E4Q34264505-C676C5B7-8F24-41B2-A18C-0F3C38979678Q34273826-6BD524BA-6E56-4A21-970B-AA1FDF66D60DQ34429053-79ABE857-C01A-4033-8E2B-BB5589E79E32Q34775877-5338BD8C-592D-4BF7-92E8-C8572E62E7EDQ34897562-47554960-37D0-4EA9-8E68-61482F8D5C7CQ34999137-16060EDD-1D0F-4D00-80D9-175DF394CACAQ35421119-151DF0C5-704D-4990-8325-D13A24EBD749
P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
p63-associated disorders.
@ast
p63-associated disorders.
@en
type
label
p63-associated disorders.
@ast
p63-associated disorders.
@en
prefLabel
p63-associated disorders.
@ast
p63-associated disorders.
@en
P356
P1433
P1476
p63-associated disorders
@en
P2093
Hans G Brunner
Tuula Rinne
P304
P356
10.4161/CC.6.3.3796
P577
2007-02-03T00:00:00Z