Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.
about
The crucial impact of lysosomes in aging and longevity"TRP inflammation" relationship in cardiovascular systemRegulation of lysosomal ion homeostasis by channels and transportersA lysosome-centered view of nutrient homeostasisTFEB at a glanceTranscriptional and epigenetic regulation of autophagy in agingBeyond indigestion: emerging roles for lysosome-based signaling in human diseaseAutophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice.Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolismAn Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host DefenseMultiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulatorA central role for calcineurin in protein misfolding neurodegenerative diseases.Lacritin and other autophagy associated proteins in ocular surface health.High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heartRecombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels.TFE3 regulates whole-body energy metabolism in cooperation with TFEB.NAADP-mediated Ca2+ signaling promotes autophagy and protects against LPS-induced liver injury.MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5CRYβA3/A1-Crystallin Knockout Develops Nuclear Cataract and Causes Impaired Lysosomal Cargo Clearance and Calpain Activation.Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy.Pompe disease: Shared and unshared features of lysosomal storage disordersCalpain Cleaves Most Components in the Multiple Aminoacyl-tRNA Synthetase Complex and Affects Their FunctionsLysosomal adaptation: How cells respond to lysosomotropic compounds.Acidic Ca2+ stores in neurodegeneration.The awesome lysosome.Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: a mechanistic insight.Intracellular sphingosine releases calcium from lysosomes.TFEB and TFE3 are novel components of the integrated stress response.AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes.ESCRT-Dependent Cell Death in a Caenorhabditis elegans Model of the Lysosomal Storage Disorder Mucolipidosis Type IV.Dysregulation of Nutrient Sensing and CLEARance in Presenilin Deficiency.The regulation of autophagy during exercise in skeletal muscleRegulation of cardiomyocyte autophagy by calcium.AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation.TPC2 controls pigmentation by regulating melanosome pH and sizeThe endoplasmic reticulum, not the pH gradient, drives calcium refilling of lysosomes.The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB PerspectiveMCOLN1 is a ROS sensor in lysosomes that regulates autophagyPromotion of Proapoptotic Signals by Lysosomal Photodamage: Mechanistic Aspects and Influence of AutophagyTFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages.
P2860
Q26749118-590BC02A-2D11-49C4-A1FD-6EA9BE1CC1BEQ26781720-8D235500-E365-4A7F-9F1D-6B2E91929403Q28069327-266050E9-8B44-439B-B985-548244E97433Q28073435-836D12D0-6F8A-4B19-82F3-5B998B0B329BQ28074375-040D72B2-A11C-4D93-9F8F-08369CF1FE11Q28083637-E5087D77-9B59-4004-ACC3-088AD37B1505Q28084027-CAD17FD9-988E-462A-8132-27A2BF001276Q28392951-3F6191F4-95C3-4844-A428-1CDAF2B5DD33Q28394996-985159B6-7F8B-4AB2-A23A-7DDF17094C1BQ28508861-C268ECBB-F20F-4E14-9678-5B2C95686732Q28854564-692E258B-A049-4A9B-A693-233194A538C0Q30245032-E3B05AAC-54BF-4991-BC0C-0FFF50333AA0Q30278788-0BD14735-AF1B-4748-9876-E664EF1D3902Q30835214-9C7C1450-9485-48CB-BAC3-707C2F8956BDQ30849715-6A6E746D-9881-47B8-B820-7C6D0ADBE682Q33625901-6DA2FAA0-74DC-4DEF-94F9-23E1043196FDQ33800621-CCBD554C-90E8-4E85-AFE5-5DFF949B34C4Q35912612-D3AE7C02-B816-434A-9EDB-730C480B2CA5Q35919942-600E6A1E-E1C8-49D0-80B9-ED4CC699DA54Q36182739-E272B15F-D6DF-4349-A728-ED2AAAA5502CQ36207744-9FD75F42-A2A7-4E7B-88AD-059FC0907265Q36283593-4F13483C-0335-47C2-8E2E-FC661F35E894Q36310581-F9BB9020-E326-430C-9E8C-685FBAF4FDD7Q36395510-73A02698-7F97-4656-A7D9-4B80F9CFCC61Q36525887-700FEB45-E28A-413D-BB93-6E50A1C05304Q36546347-FCA3D5BF-3E0F-4175-A1A3-4823B03DB43BQ36552660-52BB973C-F86B-4E16-8A39-A235B64C9844Q36635731-46D1F7A6-69B0-400D-BD8C-BA285A26D64AQ36661543-0BDDFE25-EDEA-4FE0-B42B-10817105E807Q36677308-C8F793F2-FE0D-4FB4-A122-4D4A0D9BEE2FQ36690758-450C7323-CF27-4B61-A2B6-19A75940001CQ36698649-EA315569-77D9-45BB-A5E8-D563547A922BQ36810766-7FE9E20D-C0A1-44B1-8A9C-BDCD3681CE5EQ36863748-279F6B71-BA64-41C1-813D-028B5D8E47FAQ36931154-C18945B3-8985-4F36-9150-F59BF5AB6EEAQ37008566-3AEF54BE-6995-46C1-B042-8B7F2006DCDEQ37055497-B3BDC726-FBB3-4054-B760-68E5DFCBE0BEQ37061225-C7D2FD6B-1C64-42E6-9CBB-AFBD394A36A4Q37127476-F7DF9EB2-FF60-4352-A85F-E74815F4954FQ37141750-36DA89C3-1EFC-4165-BC2E-5B002B77EC9A
P2860
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.
@ast
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.
@en
type
label
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.
@ast
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.
@en
prefLabel
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.
@ast
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.
@en
P2093
P2860
P50
P356
P1433
P1476
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.
@en
P2093
Alison Forrester
Anna Scotto-Rosato
Carolina Prezioso
Haoxing Xu
Ivana Peluso
Marco Sandri
Rosario Rizzuto
Sandro Montefusco
Simone Di Paola
P2860
P2888
P304
P356
10.1038/NCB3114
P50
P577
2015-03-01T00:00:00Z