Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors.
about
Transcriptional regulation of hepatic lipogenesisDistinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivationCoexpression of nuclear receptors and histone methylation modifying genes in the testis: implications for endocrine disruptor modes of actionBisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo.Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon.Coordinated postnatal down-regulation of multiple growth-promoting genes: evidence for a genetic program limiting organ growth.Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.Histone methylases MLL1 and MLL3 coordinate with estrogen receptors in estrogen-mediated HOXB9 expression.Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4An LXR-NCOA5 gene regulatory complex directs inflammatory crosstalk-dependent repression of macrophage cholesterol efflux.Requirement for MLL3 in p53 regulation of hepatic expression of small heterodimer partner and bile acid homeostasis.dSet1 is the main H3K4 di- and tri-methyltransferase throughout Drosophila developmentThe effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients.Histone recognition and nuclear receptor co-activator functions of Drosophila cara mitad, a homolog of the N-terminal portion of mammalian MLL2 and MLL3SETDB2 Links Glucocorticoid to Lipid Metabolism through Insig2a Regulation.Loss of Mll3 Catalytic Function Promotes Aberrant MyelopoiesisX-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific mannerMLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.Histone methyl transferases and demethylases; can they link metabolism and transcription?Nuclear receptor coactivators: structural and functional biochemistry.Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol.Poly(ADP-ribose) Polymerase 1 Represses Liver X Receptor-mediated ABCA1 Expression and Cholesterol Efflux in Macrophages.Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesisCrucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.Characterization of ASC-2 as an antiatherogenic transcriptional coactivator of liver X receptors in macrophagesMinireview: role of protein methylation and demethylation in nuclear hormone signaling.ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing.Targeting liver X receptors in human health: deadlock or promising trail?Epigenetic regulation by nuclear receptors.Epigenetic methylations and their connections with metabolism.Alterations of Histone Modifications Contribute to Pregnane X Receptor-Mediated Induction of CYP3A4 by Rifampicin.Immunometabolic Signaling Pathways Contribute to Macrophage and Dendritic Cell Function.Four enzymes cooperate to displace histone H1 during the first minute of hormonal gene activation.Acetylation- and Methylation-Related Epigenetic Proteins in the Context of Their Targets.Mixed lineage leukaemia-4 regulates cell-cycle progression and cell viability and its depletion suppresses growth of xenografted tumour in vivo.The multiple endocrine neoplasia type 1 (MEN1) tumor suppressor regulates peroxisome proliferator-activated receptor gamma-dependent adipocyte differentiation.Mixed lineage leukemia histone methylases play critical roles in estrogen-mediated regulation of HOXC13.Gene expression in superior temporal cortex of schizophrenia patients.
P2860
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P2860
Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Activating signal cointegrator ...... MLL4 to the liver X receptors.
@ast
Activating signal cointegrator ...... MLL4 to the liver X receptors.
@en
type
label
Activating signal cointegrator ...... MLL4 to the liver X receptors.
@ast
Activating signal cointegrator ...... MLL4 to the liver X receptors.
@en
prefLabel
Activating signal cointegrator ...... MLL4 to the liver X receptors.
@ast
Activating signal cointegrator ...... MLL4 to the liver X receptors.
@en
P2093
P2860
P356
P1476
Activating signal cointegrator ...... MLL4 to the liver X receptors.
@en
P2093
Jeongkyung Lee
Seunghee Lee
Soo-Kyung Lee
P2860
P304
P356
10.1210/ME.2008-0012
P577
2008-03-27T00:00:00Z