PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex. - Wikidata - awgldk - TriplyDB

PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex.

PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex.

http://www.wikidata.org/entity/Q36710785

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Requirement of the mTOR kinase for the regulation of Maf1 phosphorylation and control of RNA polymerase III-dependent transcription in cancer cells mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1 Emerging Roles for Maf1 beyond the Regulation of RNA Polymerase III Activity Regulation of pol III transcription by nutrient and stress signaling pathways High-resolution structure of TBP with TAF1 reveals anchoring patterns in transcriptional regulation Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.Integrated genomic characterization of papillary thyroid carcinoma Tamoxifen represses alcohol-induced transcription of RNA polymerase III-dependent genes in breast cancer cells Active Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In Vivo Enhanced RNA polymerase III-dependent transcription is required for oncogenic transformation Down-regulation of the transcriptional mediator subunit Med1 contributes to the loss of expression of metastasis-associated dapk1 in human cancers and cancer cells Differential expression of the TFIIIB subunits Brf1 and Brf2 in cancer cells.Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma Ribosomal DNA copy number loss and sequence variation in cancer Cell growth- and differentiation-dependent regulation of RNA polymerase III transcription.Alteration of BRCA1 expression affects alcohol-induced transcription of RNA Pol III-dependent genes.Inhibition of U6 snRNA Transcription by PTEN.Frontier of epilepsy research - mTOR signaling pathway.Phosphorylation of histone H3 serine 28 modulates RNA polymerase III-dependent transcription.Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism Differential Phosphorylation of RNA Polymerase III and the Initiation Factor TFIIIB in Saccharomyces cerevisiae.Human tRNA genes function as chromatin insulators.Drosophila RNA polymerase III repressor Maf1 controls body size and developmental timing by modulating tRNAiMet synthesis and systemic insulin signaling.Induction of proto-oncogene BRF2 in breast cancer cells by the dietary soybean isoflavone daidzein.PRC2 regulates RNA polymerase III transcribed non-translated RNA gene transcription through EZH2 and SUZ12 interaction with TFIIIC complex.The novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer's disease pathogenesis ERα mediates alcohol-induced deregulation of Pol III genes in breast cancer cells.Gender Specific Differences in RNA Polymerase III Transcription.The significance of Brf1 overexpression in human hepatocellular carcinoma Elk1 and AP-1 sites in the TBP promoter mediate alcohol-induced deregulation of Pol III-dependent genes.PTEN: a new guardian of the genome.The JNKs differentially regulate RNA polymerase III transcription by coordinately modulating the expression of all TFIIIB subunits Role of phosphorylated histone H3 serine 10 in DEN-induced deregulation of Pol III genes and cell proliferation and transformation.Epithelialization of mouse ovarian tumor cells originating in the fallopian tube stroma.Activation of mTOR: a culprit of Alzheimer's disease?Exploring a common mechanism of alcohol-induced deregulation of RNA Pol III genes in liver and breast cells.Maf1, A New PTEN Target Linking RNA and Lipid Metabolism.A weighted exact test for mutually exclusive mutations in cancer.mTOR binds to the promoters of RNA polymerase I- and III-transcribed genes.PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a.

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P2860

PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex.

http://www.wikidata.org/entity/Q36710785

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年论文

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name

PTEN represses RNA polymerase ...... targeting the TFIIIB complex.

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PTEN represses RNA polymerase ...... targeting the TFIIIB complex.

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type

label

PTEN represses RNA polymerase ...... targeting the TFIIIB complex.

@ast

PTEN represses RNA polymerase ...... targeting the TFIIIB complex.

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prefLabel

PTEN represses RNA polymerase ...... targeting the TFIIIB complex.

@ast

PTEN represses RNA polymerase ...... targeting the TFIIIB complex.

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Molecular and Cellular Biology

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PTEN represses RNA polymerase ...... targeting the TFIIIB complex.

@en

P2093

Annette Woiwode

http://www.w3.org/2001/XMLSchema#string

Cheng Zhang

http://www.w3.org/2001/XMLSchema#string

Deborah L Johnson

http://www.w3.org/2001/XMLSchema#string

Martin Teichmann

http://www.w3.org/2001/XMLSchema#string

Robert G Roeder

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Sandra A S Johnson

http://www.w3.org/2001/XMLSchema#string

Shuping Zhong

http://www.w3.org/2001/XMLSchema#string

P2860

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

Phosphorylation of the PTEN tail regulates protein stability and function

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

Ubiquitination regulates PTEN nuclear import and tumor suppression

PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

TFIIIB is phosphorylated, disrupted and selectively released from tRNA promoters during mitosis in vivo

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

Pten is essential for embryonic development and tumour suppression

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4204-4214

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10.1128/MCB.01912-07

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12

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28

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5461579

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18391023

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2423115

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