PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms - Wikidata - awgldk - TriplyDB

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

http://www.wikidata.org/entity/Q28181035

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Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance.Mitochondrial dysfunction in Pten haplo-insufficient mice with social deficits and repetitive behavior: interplay between Pten and p53 Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases Activation of p53 by MEG3 non-coding RNA CSIG inhibits PTEN translation in replicative senescence PTEN suppresses the oncogenic function of AIB1 through decreasing its protein stability via mechanism involving Fbw7 alpha Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN phosphatases PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex Network of Cancer Genes: a web resource to analyze duplicability, orthology and network properties of cancer genes Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer p53-independent endoplasmic reticulum stress-mediated cytotoxicity of a Newcastle disease virus strain in tumor cell lines Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis Mutant p53 Drives Cancer by Subverting Multiple Tumor Suppression Pathways The PTEN tumor suppressor gene and its role in lymphoma pathogenesis Focus on PTEN Regulation PTEN regulation of ERK1/2 signaling in cancer Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression A functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activity Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs Inhibition of neuronal phenotype by PTEN in PC12 cells Involvement of PTEN in TPA-mediated p53-activation in mouse skin epidermal JB6 cells Regulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein.Alternative splicing of Arabidopsis IBR5 pre-mRNA generates two IBR5 isoforms with distinct and overlapping functions.PTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7.PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations.A novel PTEN/mutant p53/c-Myc/Bcl-XL axis mediates context-dependent oncogenic effects of PTEN with implications for cancer prognosis and therapy mTOR and cancer: many loops in one pathway.Identification of genes differentially expressed between benign and osteopontin transformed rat mammary epithelial cells Methylation profile of TP53 regulatory pathway and mtDNA alterations in breast cancer patients lacking TP53 mutations.PTEN mediates Notch-dependent stalk cell arrest in angiogenesis Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer.PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3.Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc.Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor.Phosphatase and tensin homologue growth suppression without phosphatase Combined PTEN Mutation and Protein Expression Associate with Overall and Disease-Free Survival of Glioblastoma Patients.Molecular cytogenetic characterization of canine histiocytic sarcoma: A spontaneous model for human histiocytic cancer identifies deletion of tumor suppressor genes and highlights influence of genetic background on tumor behavior.Determining PTEN functional status by network component deduced transcription factor activities

P2860

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P2860

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

http://www.wikidata.org/entity/Q28181035

description

2003 nî lūn-bûn

@nan

2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի փետրվարին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

PTEN tumor suppressor regulate ...... nt and -independent mechanisms

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PTEN tumor suppressor regulate ...... nt and -independent mechanisms

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PTEN tumor suppressor regulate ...... nt and -independent mechanisms

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type

label

PTEN tumor suppressor regulate ...... nt and -independent mechanisms

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PTEN tumor suppressor regulate ...... nt and -independent mechanisms

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PTEN tumor suppressor regulate ...... nt and -independent mechanisms

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prefLabel

PTEN tumor suppressor regulate ...... nt and -independent mechanisms

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PTEN tumor suppressor regulate ...... nt and -independent mechanisms

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PTEN tumor suppressor regulate ...... nt and -independent mechanisms

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PTEN tumor suppressor regulate ...... nt and -independent mechanisms

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Andrew D Whale

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Andrew G Li

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Daniel J Freeman

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Gang Wei

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Heng-Hong Li

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Hilda Martinez-Diaz

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Hong Wu

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Nathalie Kertesz

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Nora Rozengurt

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Ralf Lesche

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117-30

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scholarly article

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3242296

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10.1016/S1535-6108(03)00021-7

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12620407

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