Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism.
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Dysregulation of Mammalian Target of Rapamycin Signaling in Mouse Models of AutismBalancing Proliferation and Connectivity in PTEN-associated Autism Spectrum DisorderPTEN: A master regulator of neuronal structure, function, and plasticitySubcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disordersSeizure-dependent mTOR activation in 5-HT neurons promotes autism-like behaviors in miceWnt signaling networks in autism spectrum disorder and intellectual disabilityAutistic-Like Traits and Cerebellar Dysfunction in Purkinje Cell PTEN Knock-Out MiceDysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismHippocampal granule cell pathology in epilepsy - a possible structural basis for comorbidities of epilepsy?Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EBActivity-dependent PI(3,5)P2 synthesis controls AMPA receptor trafficking during synaptic depression.Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic driveSynapsin IIb as a functional marker of submissive behavior.Translational control in synaptic plasticity and cognitive dysfunctionMonogenic mouse models of autism spectrum disorders: Common mechanisms and missing links.AKT activation promotes PTEN hamartoma tumor syndrome-associated cataract developmentLoss of mTOR repressors Tsc1 or Pten has divergent effects on excitatory and inhibitory synaptic transmission in single hippocampal neuron cultures.Mechanisms regulating neuronal excitability and seizure development following mTOR pathway hyperactivation.Epilepsy Mechanisms in Neurocutaneous Disorders: Tuberous Sclerosis Complex, Neurofibromatosis Type 1, and Sturge-Weber Syndrome.Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteinsDysfunctional mTORC1 Signaling: A Convergent Mechanism between Syndromic and Nonsyndromic Forms of Autism Spectrum Disorder?Heterogeneity and convergence: the synaptic pathophysiology of autism.Synaptic basis of social dysfunction: a focus on postsynaptic proteins linking group-I mGluRs with AMPARs and NMDARs.The utility of rodent models of autism spectrum disordersImproving the Dermatologic Care of Individuals with Autism: A Review of Relevant Issues and a Perspective.Autism-relevant behaviors are minimally impacted by conditional deletion of Pten in oxytocinergic neurons.Pten haploinsufficient mice show broad brain overgrowth but selective impairments in autism-relevant behavioral tests.mTOR in Brain Physiology and Pathologies.Long-term consequences of conditional genetic deletion of PTEN in the sensorimotor cortex of neonatal mice.Temporal dynamics of a homeostatic pathway controlling neural network activityDisrupted hippocampal network physiology following PTEN deletion from newborn dentate granule cells.PTEN deletion increases hippocampal granule cell excitability in male and female mice.Possible involvement of a cell adhesion molecule, Migfilin, in brain development and pathogenesis of autism spectrum disorders.Melatonin reverses the decreases in hippocampal protein serine/threonine kinases observed in an animal model of autism.Neuronal PTEN deletion in adult cortical neurons triggers progressive growth of cell bodies, dendrites, and axons.
P2860
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P2860
Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Dysregulation of synaptic plas ...... nockout mouse model of autism.
@ast
Dysregulation of synaptic plas ...... nockout mouse model of autism.
@en
type
label
Dysregulation of synaptic plas ...... nockout mouse model of autism.
@ast
Dysregulation of synaptic plas ...... nockout mouse model of autism.
@en
prefLabel
Dysregulation of synaptic plas ...... nockout mouse model of autism.
@ast
Dysregulation of synaptic plas ...... nockout mouse model of autism.
@en
P2093
P2860
P356
P1476
Dysregulation of synaptic plas ...... nockout mouse model of autism.
@en
P2093
Koichi Takeuchi
Luis F Parada
Michael J Gertner
Michael V L Bennett
R Suzanne Zukin
P2860
P304
P356
10.1073/PNAS.1222803110
P407
P577
2013-03-04T00:00:00Z