Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans. - Wikidata - awgldk - TriplyDB

Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans.

Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans.

http://www.wikidata.org/entity/Q36713732

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A regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegans Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2 Succinate dehydrogenase upregulation destabilize complex I and limits the lifespan of gas-1 mutant Primary respiratory chain disease causes tissue-specific dysregulation of the global transcriptome and nutrient-sensing signaling network Bacteria, yeast, worms, and flies: exploiting simple model organisms to investigate human mitochondrial diseases Mitochondrial dysfunction remodels one-carbon metabolism in human cells Mitochondrial respiratory chain dysfunction variably increases oxidant stress in Caenorhabditis elegans.Integrative analysis of independent transcriptome data for rare diseases Subcomplex Ilambda specifically controls integrated mitochondrial functions in Caenorhabditis elegans.Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease Regulation of metabolism in Caenorhabditis elegans longevity A universal nonmonotonic relationship between gene compactness and expression levels in multicellular eukaryotes.Integrated transcriptome analysis across mitochondrial disease etiologies and tissues improves understanding of common cellular adaptations to respiratory chain dysfunction.A Select Subset of Electron Transport Chain Genes Associated with Optic Atrophy Link Mitochondria to Axon Regeneration in Caenorhabditis elegans A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells SLR-2 and JMJC-1 regulate an evolutionarily conserved stress-response network.Mitochondrial dysfunction confers resistance to multiple drugs in Caenorhabditis elegans Natural variation in life history and aging phenotypes is associated with mitochondrial DNA deletion frequency in Caenorhabditis briggsae Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans Applications of mass spectrometry to metabolomics and metabonomics: detection of biomarkers of aging and of age-related diseases.The homeobox protein CEH-23 mediates prolonged longevity in response to impaired mitochondrial electron transport chain in C. elegans.Novel interactions between mitochondrial superoxide dismutases and the electron transport chain.Long-lived mitochondrial (Mit) mutants of Caenorhabditis elegans utilize a novel metabolism Characterization of taurine as anti-obesity agent in C. elegans.In vivo quantification reveals extensive natural variation in mitochondrial form and function in Caenorhabditis briggsae.The paradox of mitochondrial dysfunction and extended longevity.Profiling the anaerobic response of C. elegans using GC-MS Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease.Collaboration between mitochondria and the nucleus is key to long life in Caenorhabditis elegans.Regulation of life span by mitochondrial respiration: the HIF-1 and ROS connection.RNAi screens to identify components of gene networks that modulate aging in Caenorhabditis elegans.Stable isotopic profiling of intermediary metabolic flux in developing and adult stage Caenorhabditis elegans.Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes.Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease.Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice Molecular profiling of mitochondrial dysfunction in Caenorhabditis elegans Mitochondrial respiratory chain disease discrimination by retrospective cohort analysis of blood metabolites.Glutathione S-transferase mediates an ageing response to mitochondrial dysfunction In vivo metabolic flux profiling with stable isotopes discriminates sites and quantifies effects of mitochondrial dysfunction in C. elegans.Neurodevelopmental manifestations of mitochondrial disease.

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P2860

Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans.

http://www.wikidata.org/entity/Q36713732

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans.

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Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans.

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Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans.

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Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans.

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Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans.

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Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans.

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J.YMGME.2007.11.007

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Molecular Genetics and Metabolism

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Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans

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E Daikhin

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I Nissim

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J R Rosenjack

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M M Sedensky

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M Yudkoff

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P G Morgan

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Z Zhang

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P2860

Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Genome-wide RNAi screening in Caenorhabditis elegans

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

In vivo nuclear magnetic resonance studies of glutamate-gamma-aminobutyric acid-glutamine cycling in rodent and human cortex: the central role of glutamine.

Mitochondrial disease: a practical approach for primary care physicians.

Global transcription analysis of Krebs tricarboxylic acid cycle mutants reveals an alternating pattern of gene expression and effects on hypoxic and oxidative genes

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Caenorhabditis elegans

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