Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppression.
about
Protein kinase C signaling and cell cycle regulationCell cycle and hormonal control of nuclear-cytoplasmic localization of the serum- and glucocorticoid-inducible protein kinase, Sgk, in mammary tumor cells. A novel convergence point of anti-proliferative and proliferative cell signaling pathwaysNovel form of p21(WAF1/CIP1/SDI1) protein in phorbol ester-induced G2/M arrestCancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1.The role of DOC-2/DAB2 protein phosphorylation in the inhibition of AP-1 activity. An underlying mechanism of its tumor-suppressive function in prostate cancer.Biological response to phorbol ester determined by alternative G1 pathways.Increased expression of protein kinase C beta activates ERK3.Cancer-associated protein kinase C mutations reveal kinase's role as tumor suppressorProtein kinase C-beta inhibition induces apoptosis and inhibits cell cycle progression in acquired immunodeficiency syndrome-related non-hodgkin lymphoma cellsC1B domain peptide of protein kinase Cγ significantly suppresses growth of human colon cancer cells in vitro and in an in vivo mouse xenograft model through induction of cell cycle arrest and apoptosisActivation of protein kinase C isozymes is associated with post-mitotic events in intestinal epithelial cells in situ.Protein kinase C signaling mediates a program of cell cycle withdrawal in the intestinal epithelium.Chlamydomonas mutants affected in the light-dependent step of sexual differentiationHepatocyte growth factor inhibits growth of hepatocellular carcinoma cells.PKCδ activated by c-MET enhances infiltration of human glioblastoma cells through NOTCH2 signaling.Altered expression of protein kinase C, lck, and CD45 in a 12-O-tetradecanoylphorbol-13-acetate-dependent leukemic T-cell variant that expresses a high level of interleukin-2 receptor.Novel revertants of H-ras oncogene-transformed R6-PKC3 cellsThe therapeutic role of targeting protein kinase C in solid and hematologic malignancies.Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-delta subspecies.Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells.Natural resistance to apoptosis correlates with resistance to chemotherapy in colorectal cancer cells.Apoptotic induction in B-cell acute lymphoblastic leukemia cell lines treated with a protein kinase Cβ inhibitor.Effects of regulatory domains of specific isoforms of protein kinase C on growth control and apoptosis in MCF-7 breast cancer cells.Role of protein kinase C in intracellular signaling.Expression of protein kinase C beta1 confers resistance to TNFalpha- and paclitaxel-induced apoptosis in HT-29 colon carcinoma cells.Protein kinase C isoenzymes: divergence in signal transduction?The alpha isoform of protein kinase C mediates phorbol ester-induced growth inhibition and p21cip1 induction in HC11 mammary epithelial cells.Growth inhibition, enhancement of intercellular adhesion, and increased expression of carcinoembryonic antigen by overexpression of phosphoinositides-specific phospholipase C beta 1 in LS174T human colon adenocarcinoma cell line.Comparative effects of overexpression of p27Kip1 and p21Cip1/Waf1 on growth and differentiation in human colon carcinoma cells.N-myc disrupts protein kinase C-mediated signal transduction in neuroblastoma.Suppression of human melanoma cell growth and metastasis by the melanoma-associated antigen CD63 (ME491).Two closely related isoforms of protein kinase C produce reciprocal effects on the growth of rat fibroblasts. Possible molecular mechanisms.Uneven distribution of protein kinase C-alpha and -beta isozymes in human sarcomas and carcinomas.Conventional protein kinase C isoforms are not essential for cellular proliferation of a T cell lymphoma line.Staurosporine differentially inhibits glioma versus non-glioma cell lines.The role of protein kinase C (PKC) in the evolution and proliferation of malignant gliomas, and the application of PKC inhibition as a novel approach to anti-glioma therapy.Molecular evidence for the direct involvement of a protein kinase C in developmental and behavioural susceptibility to tumour-promoting phorbol esters in Caenorhabditis elegans.Towards selective pharmacological modulation of protein kinase C--opportunities for the development of novel antineoplastic agentsThe expression of PDGF-alpha but not PDGF-beta receptors is suppressed in Swiss/3T3 fibroblasts over-expressing protein kinase C-alpha.HGF upregulates and modifies subcellular distribution of proteins in colon cancer cell enterocytic differentiation.
P2860
Q21131217-A0FFE466-8CE8-44B3-83CB-BB5C65A60C9EQ28578871-3207AC72-E51C-4946-88C1-35B220539D6EQ28611448-6C6856F1-F5F7-46D6-A878-C1168786F544Q33509293-DE332DA2-7BBD-4BED-8111-4CE3E333C1B5Q33878504-B9898877-01E1-4E91-A602-C6444562B819Q34263917-B1EB2227-0D4F-41E8-A97F-DF73FD2481B3Q34379011-DA91F0C0-36CF-405E-A346-966954FC742FQ35037676-0BAABC6E-5A32-4725-846C-6D2C42820D81Q35634280-D807745E-3ADB-40AC-A492-5FC1091298E5Q36149293-30CB541B-A15B-4F52-A994-61F3695D9287Q36234552-D1CF6D44-3B8F-4B61-BAEE-C35AB1223556Q36316542-4F832923-8C01-4041-B192-B356FA1FECD0Q36443913-EB4A07DB-45E5-489F-BA6B-6DDC53CC57D7Q36774791-AD8664AA-1F9B-47A7-8476-3DFA187F2ECDQ36782617-2813C560-4692-448C-8523-4D00B8E656ECQ36809528-196E43F0-FDF6-434A-85C6-67E207DD9D81Q36819170-CE37D52C-A1CC-4EAB-981E-E36B829861C7Q36964732-287DF63E-7109-4525-9641-052383CDC95EQ37269275-BC988C26-DE73-41AD-AEB0-02AFFC19004BQ38724705-C94816A8-58F7-47DE-AB9D-DC4A8F42EBE5Q39521576-E88D11A3-C2BB-4D23-96BE-CE62E4C9691CQ39601989-3CFDE93E-6AC9-477C-9254-64591862743EQ40612385-25D03C9D-BE08-4BFA-8045-9D6632C68390Q40642485-0BF8DC04-F44B-451A-A597-ABC8DBAB0EC8Q40798494-08A825D7-2F8B-4FBE-9E87-D98A424D4435Q40902836-317635DA-D3D9-445F-BF4A-A16C47DF44DDQ40912204-1FA25A10-F583-4526-B7E2-30EFF9CA8729Q40966706-CAEAC604-C6A5-4AFF-91AF-5E2BDB0DECEAQ40976779-BB980E38-FA1A-4114-9B8E-7E671E9BF211Q41080669-11E2FB36-DA27-4CB1-8A76-9F28A8B63603Q41297484-CCE1C065-B6A3-4F64-9C1E-C740FA30084CQ41381496-A10EE2DD-4BF9-442C-9505-25FB25AD8484Q41463332-3C4A09F9-A870-4018-ACE5-816447DC421BQ41517372-8CD08AAB-DC73-4B0C-BAAE-7CAC554F1E3FQ41557450-23BEE561-BAEB-4180-A9B3-566A97226C6DQ41688724-D0F3B534-7739-4331-8210-D74B63579C8DQ42060608-0D39FE23-DA7F-4CB6-81A3-298747FE7259Q42371610-01F658E8-D94F-4E36-81AC-E40B4D797212Q42799929-19A3A2A1-934E-4495-B886-C15D0B8B6601Q43737857-9C6E63DC-D897-4BF8-B1AC-560A18A27E41
P2860
Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppression.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Overexpression of protein kina ...... ibition and tumor suppression.
@ast
Overexpression of protein kina ...... ibition and tumor suppression.
@en
type
label
Overexpression of protein kina ...... ibition and tumor suppression.
@ast
Overexpression of protein kina ...... ibition and tumor suppression.
@en
prefLabel
Overexpression of protein kina ...... ibition and tumor suppression.
@ast
Overexpression of protein kina ...... ibition and tumor suppression.
@en
P2093
P2860
P356
P1476
Overexpression of protein kina ...... ibition and tumor suppression.
@en
P2093
I B Weinstein
K M Tchou-Wong
P2860
P304
P356
10.1128/MCB.10.9.4650
P407
P577
1990-09-01T00:00:00Z