Mechanisms of chemoresistance to alkylating agents in malignant glioma. - Wikidata - awgldk - TriplyDB

Mechanisms of chemoresistance to alkylating agents in malignant glioma.

Mechanisms of chemoresistance to alkylating agents in malignant glioma.

http://www.wikidata.org/entity/Q36726010

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Low temperature plasmas as emerging cancer therapeutics: the state of play and thoughts for the future Concurrent therapy to enhance radiotherapeutic outcomes in glioblastoma Aberrant methylation of different DNA repair genes demonstrates distinct prognostic value for esophageal cancer Inter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair research DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer Bionanotechnology and the future of glioma.Restoration of sensitivity in chemo-resistant glioma cells by cold atmospheric plasma.Cytoprotective effect of the elongation factor-2 kinase-mediated autophagy in breast cancer cells subjected to growth factor inhibition.Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage.Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis.Aspirin inhibits the SHH/GLI1 signaling pathway and sensitizes malignant glioma cells to temozolomide therapy.Glioma diagnostics and biomarkers: an ongoing challenge in the field of medicine and science Genomic profiling of long non-coding RNA and mRNA expression associated with acquired temozolomide resistance in glioblastoma cells.Discordant in vitro and in vivo chemopotentiating effects of the PARP inhibitor veliparib in temozolomide-sensitive versus -resistant glioblastoma multiforme xenografts.Evaluation of O6-methylguanine-DNA methyltransferase enzyme expression effect on survival of patients with Grade 4 brain astrocytoma Clinically relevant doses of chemotherapy agents reversibly block formation of glioblastoma neurospheres.KML001, a telomere-targeting drug, sensitizes glioblastoma cells to temozolomide chemotherapy and radiotherapy through DNA damage and apoptosis.mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy.Tumor cycling hypoxia induces chemoresistance in glioblastoma multiforme by upregulating the expression and function of ABCB1 Alkylation sensitivity screens reveal a conserved cross-species functionome.Synthesis and quantitative structure-activity relationship of imidazotetrazine prodrugs with activity independent of O6-methylguanine-DNA-methyltransferase, DNA mismatch repair, and p53.SB225002 promotes mitotic catastrophe in chemo-sensitive and -resistant ovarian cancer cells independent of p53 status in vitro Temozolomide in malignant glioma Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage.CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma.Salinomycin inhibits the tumor growth of glioma stem cells by selectively suppressing glioma-initiating cells.YY1 suppresses FEN1 over-expression and drug resistance in breast cancer Growth-inhibitory and chemosensitizing effects of the glutathione-S-transferase-π-activated nitric oxide donor PABA/NO in malignant gliomas.Chemoresistance of glioblastoma cancer stem cells--much more complex than expected.Overcoming the challenges in the effective delivery of chemotherapies to CNS solid tumors.Proteomic analysis of glioma chemoresistance.Base excision repair: contribution to tumorigenesis and target in anticancer treatment paradigms Extracellular RNAs: development as biomarkers of human disease.Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.Tumor Suppressor WWOX and p53 Alterations and Drug Resistance in Glioblastomas.Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins.FoxM1 inhibition sensitizes resistant glioblastoma cells to temozolomide by downregulating the expression of DNA-repair gene Rad51.

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P2860

Mechanisms of chemoresistance to alkylating agents in malignant glioma.

http://www.wikidata.org/entity/Q36726010

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Mechanisms of chemoresistance to alkylating agents in malignant glioma.

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Mechanisms of chemoresistance to alkylating agents in malignant glioma.

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type

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Mechanisms of chemoresistance to alkylating agents in malignant glioma.

@ast

Mechanisms of chemoresistance to alkylating agents in malignant glioma.

@en

prefLabel

Mechanisms of chemoresistance to alkylating agents in malignant glioma.

@ast

Mechanisms of chemoresistance to alkylating agents in malignant glioma.

@en

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Clinical Cancer Research

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Mechanisms of chemoresistance to alkylating agents in malignant glioma.

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C David James

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Gaspar J Kitange

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Hilary Calvert

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Jann N Sarkaria

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Ruth Plummer

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P2860

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

MGMT gene silencing and benefit from temozolomide in glioblastoma.

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Repair of DNA containing O6-alkylguanine

Mechanisms of human DNA repair: an update

Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents.

Effect of O6-benzylguanine on alkylating agent-induced toxicity and mutagenicity. In Chinese hamster ovary cells expressing wild-type and mutant O6-alkylguanine-DNA alkyltransferases.

Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.

Characterization of MLH1 and MSH2 DNA mismatch repair proteins in cell lines of the NCI anticancer drug screen.

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