Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans. - Wikidata - awgldk - TriplyDB

Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans.

Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans.

http://www.wikidata.org/entity/Q36726189

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Role of Hedgehog Signaling Pathway in NASH Revisiting Epithelial-to-Mesenchymal Transition in Liver Fibrosis: Clues for a Better Understanding of the "Reactive" Biliary Epithelial Phenotype Adult Hepatic Progenitor Cell Niche: How it affects the Progenitor Cell Fate Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer Alcoholic liver disease: pathogenesis and new therapeutic targets.Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways Hepatic stellate cells express thymosin Beta 4 in chronically damaged liver Evolving therapies for liver fibrosis.Alcohol activates the hedgehog pathway and induces related procarcinogenic processes in the alcohol-preferring rat model of hepatocarcinogenesis.New drug targets for alcoholic liver disease.Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis Fibrosis-dependent mechanisms of hepatocarcinogenesis Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice.Foxl1 is a marker of bipotential hepatic progenitor cells in mice.Expression of deleted in malignant brain tumours 1 (DMBT1) relates to the proliferation and malignant transformation of hepatic progenitor cells in hepatitis B virus-related liver diseases.Role for hedgehog pathway in regulating growth and function of invariant NKT cells.Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway.Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma.Col1A1 production and apoptotic resistance in TGF-β1-induced epithelial-to-mesenchymal transition-like phenotype of 603B cells.Effects of long-term ethanol administration in a rat total enteral nutrition model of alcoholic liver disease New concepts in liver regeneration.Crosstalk between Shh and TGF-β signaling in cyclosporine-enhanced cell proliferation in human gingival fibroblasts.Stem cells and liver regeneration.The biliary epithelium gives rise to liver progenitor cells The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice Hepatitis C virus infection: establishment of chronicity and liver disease progression Interleukin-22 promotes proliferation of liver stem/progenitor cells in mice and patients with chronic hepatitis B virus infection Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease.Ethanol administration impairs pancreatic repair after injury.Chronic ethanol feeding alters miRNA expression dynamics during liver regeneration.The origin, biology, and therapeutic potential of facultative adult hepatic progenitor cells.Macrophage-derived Hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni.Molecular mechanisms of ethanol-associated oro-esophageal squamous cell carcinoma.Increased production of sonic hedgehog by ballooned hepatocytes.Hedgehog signaling in cholangiocytes.Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans.Alcohol consumption negates estrogen-mediated myocardial repair in ovariectomized mice by inhibiting endothelial progenitor cell mobilization and function.MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice Alcohol Disrupts Human Liver Stem/Progenitor Cell Proliferation and Differentiation.Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production.

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Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans.

http://www.wikidata.org/entity/Q36726189

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J.GASTRO.2008.02.022

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Gastroenterology

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Accumulation of hedgehog-respo ...... e severity in mice and humans.

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Alessia Omenetti

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Anna Mae Diehl

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Ian N Hines

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Kevin D Brown

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Laura Rubbia-Brandt

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Laurent Spahr

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Liu Yang

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Margon Vandongen

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Rafal P Witek

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Richard A Rippe

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P2860

WNT antagonist, SFRP1, is Hedgehog signaling target

Sonic hedgehog signaling regulates Gli3 processing, mesenchymal proliferation, and differentiation during mouse lung organogenesis

Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors

Extracellular modulation of the Hedgehog, Wnt and TGF-beta signalling pathways during embryonic development.

MELD accurately predicts mortality in patients with alcoholic hepatitis.

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling.

Hepatic progenitor cells in human liver diseases.

Pathogenesis and management of alcoholic hepatitis.

Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver disease

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