Identification and functional characterization of the human T-cell receptor beta gene transcriptional enhancer: common nuclear proteins interact with the transcriptional regulatory elements of the T-cell receptor alpha and beta genes.
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A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cellsMurine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancerThe ht beta gene encodes a novel CACCC box-binding protein that regulates T-cell receptor gene expressionThe high mobility group transcription factor, SOX4, transactivates the human CD2 enhancerA T-cell specific TCR delta DNA binding protein is a member of the human GATA familyIdentification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactionsThe human enhancer-binding protein Gata3 binds to several T-cell receptor regulatory elementsHuman GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha geneMolecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response elementExpression of the Runt domain-encoding PEBP2 alpha genes in T cells during thymic developmentThe Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteinscis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.Chromosomal translocations joining LCK and TCRB loci in human T cell leukemia.Genomic analysis reveals extensive gene duplication within the bovine TRB locus.Nuclear structure/gene expression interrelationships.Members of the GATA family of transcription factors bind to the U3 region of Cas-Br-E and graffi retroviruses and transactivate their expression.Inhibition of T-cell receptor beta-chain gene rearrangement by overexpression of the non-receptor protein tyrosine kinase p56lck.Definition of a T-cell receptor beta gene core enhancer of V(D)J recombination by transgenic mapping.TCR beta and TCR alpha gene enhancers confer tissue- and stage-specificity on V(D)J recombination events.An enhancer LEF-1/TCF-1 site is essential for insertion site-independent transgene expression in thymusGenome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene familyp70 lupus autoantigen binds the enhancer of the T-cell receptor beta-chain geneThe genomic structure of human V beta 6 T cell antigen receptor genes.Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors.Turning T-cell receptor beta recombination on and off: more questions than answers.PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene.Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding proteinThe t(12;21) translocation converts AML-1B from an activator to a repressor of transcription.Chromosome walking on the TCL1 locus involved in T-cell neoplasia.Functional analysis of the V gamma 3 promoter of the murine gamma delta T-cell receptorCooperative binding of Ets-1 and core binding factor to DNAA novel myogenic regulatory circuit controls slow/cardiac troponin C gene transcription in skeletal muscle.The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation.A novel POU domain protein which binds to the T-cell receptor beta enhancer.Identification and characterization of a T-cell-specific enhancer adjacent to the murine CD4 gene.Identification and characterization of a cardiac-specific transcriptional regulatory element in the slow/cardiac troponin C gene.A phorbol ester response element within the human T-cell receptor beta-chain enhancer.Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis.Molecular mechanisms that control mouse and human TCR-alphabeta and TCR-gammadelta T cell development.Binding of thymic factors to the conserved decanucleotide promoter element of the T-cell receptor V beta gene is developmentally regulated and is absent in SCID mice.
P2860
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P2860
Identification and functional characterization of the human T-cell receptor beta gene transcriptional enhancer: common nuclear proteins interact with the transcriptional regulatory elements of the T-cell receptor alpha and beta genes.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Identification and functional ...... receptor alpha and beta genes.
@ast
Identification and functional ...... receptor alpha and beta genes.
@en
type
label
Identification and functional ...... receptor alpha and beta genes.
@ast
Identification and functional ...... receptor alpha and beta genes.
@en
prefLabel
Identification and functional ...... receptor alpha and beta genes.
@ast
Identification and functional ...... receptor alpha and beta genes.
@en
P2860
P356
P1476
Identification and functional ...... receptor alpha and beta genes.
@en
P2093
J M Leiden
L R Gottschalk
P2860
P304
P356
10.1128/MCB.10.10.5486
P407
P577
1990-10-01T00:00:00Z