RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A
about
Dinosaurs and ancient civilizations: reflections on the treatment of cancerSimilar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistanceAre KRAS/BRAF mutations potent prognostic and/or predictive biomarkers in colorectal cancers?Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cellsData Mining Approaches for Genomic Biomarker Development: Applications Using Drug Screening Data from the Cancer Genome Project and the Cancer Cell Line EncyclopediaNeoplasia: the second decade.Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin.DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset.The NF1 somatic mutational landscape in sporadic human cancers.Neoplasms associated with germline and somatic NF1 gene mutationsThe NF1 gene revisited - from bench to bedside.Temporal dissection of K-ras(G12D) mutant in vitro and in vivo using a regulatable K-ras(G12D) mouse alleleAn unbalanced maternal diet in pregnancy associates with offspring epigenetic changes in genes controlling glucocorticoid action and foetal growth.BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancerInfluence of microsatellite instability and KRAS and BRAF mutations on lymph node harvest in stage I-III colon cancers.Clinico-pathological and biomolecular findings in Italian patients with multiple cutaneous neurofibromas.Molecular subtypes in stage II-III colon cancer defined by genomic instability: early recurrence-risk associated with a high copy-number variation and loss of RUNX3 and CDKN2A.MicroRNA Expression Signatures Associated With BRAF-Mutated Versus KRAS-Mutated Colorectal Cancers.Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutationsLoss of RASSF1A expression in colorectal cancer and its association with K-ras status.JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype.Gene expression deregulation by KRAS G12D and G12V in a BRAF V600E context.Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers.Aurora-A expression is independently associated with chromosomal instability in colorectal cancer.The War on Cancer rages on.Colorectal cancer and RASSF family--a special emphasis on RASSF1A.RAS signaling pathways, mutations and their role in colorectal cancerDNA methylation and apoptosis resistance in cancer cellsValproic acid enhances bosutinib cytotoxicity in colon cancer cells.Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors.Methylation status of the APC and RASSF1A promoter in cell-free circulating DNA and its prognostic role in patients with colorectal cancer.Association between clinicopathological characteristics and RAS mutation in colorectal cancer.BRAF mutation is a prognostic biomarker for colorectal liver metastasectomy.A robust targeted sequencing approach for low input and variable quality DNA from clinical samples.An Unusual Combination: KRAS and BRAF Co-mutated Metastatic Colorectal Cancer.Prognostic relevance of occult metastases detected by cytokeratin 20 and mucin 2 mRNA levels in sentinel lymph nodes from colon cancer patients.Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer.Clinicopathological and protein characterization of BRAF- and K-RAS-mutated colorectal cancer and implications for prognosis.Overexpression of ST5, an activator of Ras, has no effect on β-cell proliferation in adult mice.
P2860
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P2860
RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
RAS signaling in colorectal ca ...... RAS, RAF, NF1, and/or RASSF1A
@ast
RAS signaling in colorectal ca ...... RAS, RAF, NF1, and/or RASSF1A
@en
type
label
RAS signaling in colorectal ca ...... RAS, RAF, NF1, and/or RASSF1A
@ast
RAS signaling in colorectal ca ...... RAS, RAF, NF1, and/or RASSF1A
@en
prefLabel
RAS signaling in colorectal ca ...... RAS, RAF, NF1, and/or RASSF1A
@ast
RAS signaling in colorectal ca ...... RAS, RAF, NF1, and/or RASSF1A
@en
P2093
P2860
P356
P1433
P1476
RAS signaling in colorectal ca ...... RAS, RAF, NF1, and/or RASSF1A
@en
P2093
Gunn I Meling
Guro E Lind
Irene Bottillo
Stine A Danielsen
Terje Ahlquist
Torleiv O Rognum
P2860
P304
680-6, 2 p following 686
P356
10.1593/NEO.08312
P577
2008-07-01T00:00:00Z