Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice - Wikidata - awgldk - TriplyDB

Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice

Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice

http://www.wikidata.org/entity/Q36731891

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Breaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression.The TLR and IL-1 signalling network at a glance Cross-Talk between Shp1 and PIPKIγ Controls Leukocyte Recruitment.Expression of the TEL-Syk fusion protein in hematopoietic stem cells leads to rapidly fatal myelofibrosis in mice The role of dendritic cells in autoimmunity Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.Shp1 signalling is required to establish the long-lived bone marrow plasma cell pool.SHP-1 and IL-1α conspire to provoke neutrophilic dermatoses.Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice.Beyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory disease The Role of Dendritic Cell Subsets and Innate Immunity in the Pathogenesis of Type 1 Diabetes and Other Autoimmune Diseases.The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced Myeloid Cell Recruitment into the Lung and Their Ability To Secrete Chemokines.MET is required for the recruitment of anti-tumoural neutrophils Protein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b Degradation LynA regulates an inflammation-sensitive signaling checkpoint in macrophages.Lacrimal Gland Inflammation Deregulates Extracellular Matrix Remodeling and Alters Molecular Signature of Epithelial Stem/Progenitor Cells.Snake Venom Disintegrin Inhibits the Activation of Toll-Like Receptors and Alleviates Sepsis through Integrin alphaVbeta3 Blockade.Neutrophils in animal models of autoimmune disease Genome-wide analysis of the genetic regulation of gene expression in human neutrophils.Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammation Purity of transferred CD8(+) T cells is crucial for safety and efficacy of combinatorial tumor immunotherapy in the absence of SHP-1.Akt and SHP-1 are DC-intrinsic checkpoints for tumor immunity.LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity.B cell-specific loss of Lyn kinase leads to autoimmunity In vitro studies implicate an imbalanced activation of dendritic cells in the pathogenesis of murine autoimmune pancreatitis.Genetic dissection of dendritic cell homeostasis and function: lessons from cell type-specific gene ablation Regulation of neutrophil functions through inhibitory receptors: an emerging paradigm in health and disease.Lyn and Fyn function as molecular switches that control immunoreceptors to direct homeostasis or inflammation Mechanism of Diapedesis: Importance of the Transcellular Route.SHP-1: the next checkpoint target for cancer immunotherapy?MicroRNAs in neutrophils: potential next generation therapeutics for inflammatory ailments.Protein tyrosine phosphatase SHP-1: resurgence as new drug target for human autoimmune disorders.Shp1 function in myeloid cells.Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide.Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection Animal models: unravelling the motheaten phenotype.Role of negative regulation of immune signaling pathways in neutrophil function.Neutrophil derived CSF1 induces macrophage polarization and promotes transplantation tolerance.ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis.SHP-1 (PTPN6) keeps the inflammation at bay: limiting IL-1α-mediated neutrophilic dermatoses by preventing Syk kinase activation.

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P2860

Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice

http://www.wikidata.org/entity/Q36731891

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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name

Distinct roles for neutrophils ...... autoimmunity in motheaten mice

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Distinct roles for neutrophils ...... autoimmunity in motheaten mice

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Distinct roles for neutrophils ...... autoimmunity in motheaten mice

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Distinct roles for neutrophils ...... autoimmunity in motheaten mice

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Distinct roles for neutrophils ...... autoimmunity in motheaten mice

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Distinct roles for neutrophils ...... autoimmunity in motheaten mice

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J.IMMUNI.2013.02.018

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Distinct roles for neutrophils ...... autoimmunity in motheaten mice

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Benjamin G Neel

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Clare L Abram

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Clifford A Lowell

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Gray L Roberge

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Lily I Pao

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P2860

Identification of major binding proteins and substrates for the SH2-containing protein tyrosine phosphatase SHP-1 in macrophages

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs

Regulation of colony-stimulating factor 1 receptor signaling by the SH2 domain-containing tyrosine phosphatase SHPTP1

Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury.

Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling.

SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells

Toll-like receptors in systemic autoimmune disease.

Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans

Alteration in the gene encoding protein tyrosine phosphatase nonreceptor type 6 (PTPN6/SHP1) may contribute to neutrophilic dermatoses.

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