Chromatin decouples promoter threshold from dynamic range
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Unstable tandem repeats in promoters confer transcriptional evolvabilityActivity motifs reveal principles of timing in transcriptional control of the yeast metabolic networkActive VSG expression sites in Trypanosoma brucei are depleted of nucleosomesPredicting nucleosome positions on the DNA: combining intrinsic sequence preferences and remodeler activitiesEpigenetic principles and mechanisms underlying nervous system functions in health and diseaseThe prolactin gene: a paradigm of tissue-specific gene regulation with complex temporal transcription dynamicsTranscription goes digitalInterplay between gene expression noise and regulatory network architectureControl of relative timing and stoichiometry by a master regulatorReal-time quantification of protein expression at the single-cell level via dynamic protein synthesis translocation reporters.Epigenetic and conventional regulation is distributed among activators of FLO11 allowing tuning of population-level heterogeneity in its expressionThe yeast RNA polymerase II-associated factor Iwr1p is involved in the basal and regulated transcription of specific genes.The RSC chromatin remodelling enzyme has a unique role in directing the accurate positioning of nucleosomesChromatin regulation at the frontier of synthetic biologyHIV promoter integration site primarily modulates transcriptional burst size rather than frequencyInterplay between chromatin state, regulator binding, and regulatory motifs in six human cell typesSignal-dependent dynamics of transcription factor translocation controls gene expression.Promoter decoding of transcription factor dynamics involves a trade-off between noise and control of gene expressionThe chromosomal high-affinity binding sites for the Drosophila dosage compensation complex.FISim: a new similarity measure between transcription factor binding sites based on the fuzzy integralDNA specificity determinants associate with distinct transcription factor functionsHigh-resolution nucleosome mapping reveals transcription-dependent promoter packaging.Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate.Temporal dynamics and transcriptional control using single-cell gene expression analysisGenome-wide views of chromatin structureEpigenetic control of immunityDissecting the Relation between a nuclear receptor and GATA: binding affinity studies of thyroid hormone receptor and GATA2 on TSHβ promoter.Nucleosome positioning: how is it established, and why does it matter?Defining mechanisms that regulate RNA polymerase II transcription in vivoEvolution of reduced co-activator dependence led to target expansion of a starvation response pathway.Dynamic changes in genome-wide histone H3 lysine 4 methylation patterns in response to dehydration stress in Arabidopsis thaliana.An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs.Design of synthetic yeast promoters via tuning of nucleosome architecture.Nucleosome-depleted regions in cell-cycle-regulated promoters ensure reliable gene expression in every cell cycle.Genome-wide landscape of position effects on heterogeneous gene expression in Saccharomyces cerevisiae.Using targeted chromatin regulators to engineer combinatorial and spatial transcriptional regulationNucleosome occupancy landscape and dynamics at mouse recombination hotspots.The role of nucleosome positioning in the evolution of gene regulation.Contribution of transcription factor binding site motif variants to condition-specific gene expression patterns in budding yeastStochastic modeling for the expression of a gene regulated by competing transcription factors.
P2860
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P2860
Chromatin decouples promoter threshold from dynamic range
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Chromatin decouples promoter threshold from dynamic range
@ast
Chromatin decouples promoter threshold from dynamic range
@en
type
label
Chromatin decouples promoter threshold from dynamic range
@ast
Chromatin decouples promoter threshold from dynamic range
@en
prefLabel
Chromatin decouples promoter threshold from dynamic range
@ast
Chromatin decouples promoter threshold from dynamic range
@en
P2093
P2860
P356
P1433
P1476
Chromatin decouples promoter threshold from dynamic range
@en
P2093
David J Steger
Erin K O'Shea
Felix H Lam
P2860
P2888
P304
P356
10.1038/NATURE06867
P407
P577
2008-04-16T00:00:00Z
P5875
P6179
1014619205