Blockade of individual Notch ligands and receptors controls graft-versus-host disease - Wikidata - awgldk - TriplyDB

Blockade of individual Notch ligands and receptors controls graft-versus-host disease

Blockade of individual Notch ligands and receptors controls graft-versus-host disease

http://www.wikidata.org/entity/Q36733439

about

Notch signaling: its roles and therapeutic potential in hematological malignancies Acute graft-versus-host disease: a bench-to-bedside update.Notch as a Driver of Gastric Epithelial Cell Proliferation.Rescue of notch-1 signaling in antigen-specific CD8+ T cells overcomes tumor-induced T-cell suppression and enhances immunotherapy in cancer Notch activation as a driver of osteogenic sarcoma.Notch signaling at later stages of NK cell development enhances KIR expression and functional maturation Structural biology. Structural basis for Notch1 engagement of Delta-like 4 Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice.Phase 2 study of RO4929097, a gamma-secretase inhibitor, in metastatic melanoma: SWOG 0933.Notch signaling regulates antigen sensitivity of naive CD4+ T cells by tuning co-stimulation.Transient blockade of delta-like Notch ligands prevents allograft rejection mediated by cellular and humoral mechanisms in a mouse model of heart transplantation.The NOTCH signaling pathway in normal and malignant blood cell production.Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration.Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling.Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention.Programming of donor T cells using allogeneic δ-like ligand 4-positive dendritic cells to reduce GVHD in mice.ADAM Proteases and Gastrointestinal Function.Notch signaling regulates T cell accumulation and function in the central nervous system during experimental autoimmune encephalomyelitis.Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis.Notch signaling in hematopoietic cell transplantation and T cell alloimmunity.The histone methyltransferase Ezh2 is a crucial epigenetic regulator of allogeneic T-cell responses mediating graft-versus-host disease IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity.Notch signaling in skeletal stem cells.Notch Ligand DLL4 Alleviates Allergic Airway Inflammation via Induction of a Homeostatic Regulatory Pathway.Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.Therapeutic modulation of Notch signalling--are we there yet?Cellular and molecular mechanisms in graft-versus-host disease.Notch regulation of gastrointestinal stem cells.Tregs: hype or hope for allogeneic hematopoietic stem cell transplantation?Combinatorial microenvironmental regulation of liver progenitor differentiation by Notch ligands, TGFβ, and extracellular matrix.Targeting the Notch Pathway to Prevent Rejection.Notch Signaling and Alloreactivity.DLL4+ dendritic cells: Key regulators of Notch Signaling in effector T cell responses Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner.Notch Signaling in T Helper Cell Subsets: Instructor or Unbiased Amplifier?Role of ADAM10 in intestinal crypt homeostasis and tumorigenesis.Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis.T Cell-Restricted Notch Signaling Contributes to Pulmonary Th1 and Th2 Immunity during Cryptococcus neoformans Infection.Cutting Edge: Notch Signaling Promotes the Plasticity of Group-2 Innate Lymphoid Cells.Notch Ligand Delta-like 4 Promotes Regulatory T Cell Identity in Pulmonary Viral Infection.

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P2860

Blockade of individual Notch ligands and receptors controls graft-versus-host disease

http://www.wikidata.org/entity/Q36733439

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

@zh-tw

2013年论文

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2013年论文

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2013年论文

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name

Blockade of individual Notch ligands and receptors controls graft-versus-host disease

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Blockade of individual Notch ligands and receptors controls graft-versus-host disease

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type

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Blockade of individual Notch ligands and receptors controls graft-versus-host disease

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Blockade of individual Notch ligands and receptors controls graft-versus-host disease

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prefLabel

Blockade of individual Notch ligands and receptors controls graft-versus-host disease

@ast

Blockade of individual Notch ligands and receptors controls graft-versus-host disease

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Journal of Clinical Investigation

P1476

Blockade of individual Notch ligands and receptors controls graft-versus-host disease

@en

P2093

Alexis J Carulli

http://www.w3.org/2001/XMLSchema#string

Amy Shelton

http://www.w3.org/2001/XMLSchema#string

Ann Friedman

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Ashley R Sandy

http://www.w3.org/2001/XMLSchema#string

Christian W Siebel

http://www.w3.org/2001/XMLSchema#string

Gloria T Shan

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Ivy T Tran

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Jooho Chung

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Linda C Samuelson

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Minhong Yan

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P2860

Therapeutic antibody targeting of individual Notch receptors

Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo

Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells

The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands

Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

The canonical Notch signaling pathway: unfolding the activation mechanism.

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice.

The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease

P304

1590-1604

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scholarly article

P356

10.1172/JCI65477

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4

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123

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Christen L Ebens

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2013-04-01T00:00:00Z

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235775797

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23454750

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3613915

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