The histone methyltransferase Ezh2 is a crucial epigenetic regulator of allogeneic T-cell responses mediating graft-versus-host disease
about
Regulation of T Cell Differentiation and Function by EZH2Hsp90 inhibition destabilizes Ezh2 protein in alloreactive T cells and reduces graft-versus-host disease in miceEzh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice.Epigenetic enzymes are the therapeutic targets for CD4(+)CD25(+/high)Foxp3(+) regulatory T cellsAdvances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantationEZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion.Inhibition of EZH2 expression is associated with the proliferation, apoptosis, and migration of SW620 colorectal cancer cells in vitro.DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrityRegulatory T-Cell Therapy for Graft-versus-host Disease.Deciphering the epigenetic code of T lymphocytes.Regulation of CD4 T-cell differentiation and inflammation by repressive histone methylation.Epigenetic drug discovery: breaking through the immune barrier.Emerging Role for Methylation in Multiple Sclerosis: Beyond DNA.Impact of Enhancer of Zeste Homolog 2 on T Helper Cell-Mediated Allergic Rhinitis.The tumor microenvironment disarms CD8+ T lymphocyte function via a miR-26a-EZH2 axis.Inhibition of EZH2 expression is associated with the proliferation, apoptosis and migration of SW620 colorectal cancer cells in vitroSerum and Extracellular Vesicle MicroRNAs miR-423, miR-199, and miR-93* As Biomarkers for Acute Graft-versus-Host Disease.Life and Death of Activated T Cells: How Are They Different from Naïve T Cells?
P2860
Q26747390-4BBDA1A3-6B20-4925-9DA8-A0D47FCC0932Q33707337-A8EE4A9F-EC64-4B45-9072-37DDABCF0C57Q33824617-A813D01A-1880-458F-8BBF-F9CDB1C06059Q34656908-59165BB2-06F4-4559-9807-B691C70ADAB8Q35586614-7C3EF65D-72BB-4B8C-BCA9-B02AFC1F9366Q35758563-551F13B7-D4E6-471A-B749-5986E876A6B4Q37071469-F68A0656-327E-4F18-B988-0B28192BF48FQ37151491-E35B9AD3-8BE0-4FEF-AED2-CD055578585CQ37309438-8C85955A-DC09-487C-99C7-C3F832A2CBEBQ38239864-6C5F11BD-0805-4B7F-BAB9-BADB8B237D70Q38315887-62FA058C-BABA-4D04-B964-2940C8BFAD06Q38986705-454B3CE6-0956-4BF4-A686-C5DA1B049F7EQ39288872-6DFD122C-E64C-4533-BCCF-101E7D12B07EQ40963902-E3F4FAA1-66CF-43F7-893F-62882977A30AQ42333838-A2BDAE18-D86F-4396-A588-319A715C0A82Q42429965-D51D3220-9452-43E7-8326-658A67536786Q47158588-4A9F1687-2325-43AB-A2D6-AC6FB81B10CBQ49636303-B00A3C71-D020-48C1-B3CC-483A82ABC677
P2860
The histone methyltransferase Ezh2 is a crucial epigenetic regulator of allogeneic T-cell responses mediating graft-versus-host disease
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 October 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The histone methyltransferase ...... ting graft-versus-host disease
@en
The histone methyltransferase ...... ing graft-versus-host disease.
@nl
type
label
The histone methyltransferase ...... ting graft-versus-host disease
@en
The histone methyltransferase ...... ing graft-versus-host disease.
@nl
prefLabel
The histone methyltransferase ...... ting graft-versus-host disease
@en
The histone methyltransferase ...... ing graft-versus-host disease.
@nl
P2093
P2860
P1433
P1476
The histone methyltransferase ...... ting graft-versus-host disease
@en
P2093
Arul M Chinnaiyan
Izumi Mochizuki
Kazuhiro Mochizuki
Pavan Reddy
Philip D King
Philip E Lapinski
Shin Mineishi
P2860
P304
P356
10.1182/BLOOD-2013-05-505180
P407
P50
P577
2013-10-18T00:00:00Z