The biology and therapeutic potential of interleukin 27.
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Interleukin-27: balancing protective and pathological immunityMolecules altering the intracellular thiol content modulate NF-kB and STAT-1/IRF-1 signalling pathways and IL-12 p40 and IL-27 p28 production in murine macrophagesIL-31-IL-31R interactions limit the magnitude of Th2 cytokine-dependent immunity and inflammation following intestinal helminth infectionDecreased expression of interleukin-27 in immune thrombocytopenia.Failure of interferon gamma to induce the anti-inflammatory interleukin 18 binding protein in familial hemophagocytosisPlasma interleukin-27 (IL-27) levels are not modulated in patients with chronic HIV-1 infectionHigh Interleukin 27 Production is Associated with Early Clinical Stage and Localized Disease in Patients with Melanoma.Interleukin-27, an anti-HIV-1 cytokine, inhibits replication of hepatitis C virusRole of interleukin 10 transcriptional regulation in inflammation and autoimmune diseaseIL-27 structural analysis demonstrates similarities with ciliary neurotrophic factor (CNTF) and leads to the identification of antagonistic variantsCell origins and diagnostic accuracy of interleukin 27 in pleural effusions.IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells.IL-27-induced gene expression is downregulated in HIV-infected subjects.Suppression of TNF-α and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27IL-27 promotes T cell-dependent colitis through multiple mechanisms.Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3.Interleukin-27 signaling promotes immunity against endogenously arising murine tumors.A role for IL-27p28 as an antagonist of gp130-mediated signaling.The IL-27 receptor has biphasic effects in crescentic glomerulonephritis mediated through Th1 responses.IL-27 imparts immunoregulatory function to human NK cell subsets.The association between single nucleotide polymorphism in interleukin-27 gene and recurrent pregnancy loss in Iranian womenInfluenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signalingComplement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages.The analysis of correlation between IL-12 gene expression and hepatitis B virus in the affected patients.Interleukin-12 and tuberculosis: an old story revisitedEpstein-Barr virus-induced gene 3 negatively regulates neuroinflammation and T cell activation following coronavirus-induced encephalomyelitis.Gene therapy using IL-27 ameliorates Sjögren's syndrome-like autoimmune exocrinopathy.Immune responses to inhalant allergens.The role of IL-27 in the induction of anti-tumor cytotoxic T lymphocyte responseAdvances in understanding the anti-inflammatory properties of IL-27.Modulation of inflammation by interleukin-27.Interleukin-27 inhibition of HIV-1 involves an intermediate induction of type I interferon.Regulation and function of proinflammatory TH17 cells.Evaluating the potential of IL-27 as a novel therapeutic agent in HIV-1 infection.New directions in the basic and translational biology of interleukin-27.Cytokines in the balance of protection and pathology during mycobacterial infections.Neuroendocrine Modulation of IL-27 in Macrophages.The Effects of Hypoxia on U937 Cell Line in Mesenchymal Stem Cells Co-Culture System.Interleukin-27 acts on hepatic stellate cells and induces signal transducer and activator of transcription 1-dependent responses.Interleukin-27 induces a STAT1/3- and NF-kappaB-dependent proinflammatory cytokine profile in human monocytes.
P2860
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P2860
The biology and therapeutic potential of interleukin 27.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The biology and therapeutic potential of interleukin 27.
@ast
The biology and therapeutic potential of interleukin 27.
@en
type
label
The biology and therapeutic potential of interleukin 27.
@ast
The biology and therapeutic potential of interleukin 27.
@en
prefLabel
The biology and therapeutic potential of interleukin 27.
@ast
The biology and therapeutic potential of interleukin 27.
@en
P2860
P1476
The biology and therapeutic potential of interleukin 27.
@en
P2093
Marcel Batten
P2860
P2888
P304
P356
10.1007/S00109-007-0164-7
P577
2007-02-10T00:00:00Z