Cell-specific responses to loss of cyclin-dependent kinases.
about
Cyclin D as a therapeutic target in cancerMitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant miceCdk2 is required for p53-independent G2/M checkpoint control.Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cellsCell cycle regulation by MicroRNAs in embryonic stem cellsNovel markers of left ventricular hypertrophy in uremia.Antitumor effects of flavopiridol on human uterine leiomyoma in vitro and in a xenograft model.Cdk2-null mice are resistant to ErbB-2-induced mammary tumorigenesis.T160‐phosphorylated CDK2 defines threshold for HGF dependent proliferation in primary hepatocytesCyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration.Hematopoiesis and thymic apoptosis are not affected by the loss of Cdk2.A crosstalk imbalance between p27(Kip1) and its interacting molecules enhances breast carcinogenesisp21 Inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint.Induction of G1 cell cycle arrest and cyclin D1 down-regulation in response to pericarp extract of Baneh in human breast cancer T47D cells.Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis.The effect of the cyclin-dependent kinase inhibitor flavopiridol on anaplastic large cell lymphoma cells and relationship with NPM-ALK kinase expression and activity.Cdk2 plays a critical role in hepatocyte cell cycle progression and survival in the setting of cyclin D1 expression in vivo.Altered expression of G1/S phase cell cycle regulators in placental mesenchymal stromal cells derived from preeclamptic pregnancies with fetal-placental compromise.An overview of stress response and hypometabolic strategies in Caenorhabditis elegans: conserved and contrasting signals with the mammalian system.Distinct proliferative and transcriptional effects of the D-type cyclins in vivo.Epigenetic memory in the context of nuclear reprogramming and cancer.The miR-290-295 cluster as multi-faceted players in mouse embryonic stem cellsNew perspectives for prostate cancer treatment: in vitro inhibition of LNCaP and PC3 cell proliferation by amnion-derived mesenchymal stromal cells conditioned media.Mimicking Muscle Stem Cell Quiescence in Culture: Methods for Synchronization in Reversible Arrest.Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signalingLin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells.Anchorage-independent growth of pocket protein-deficient murine fibroblasts requires bypass of G2 arrest and can be accomplished by expression of TBX2.Cyclin-dependent kinase 2 negatively regulates human pregnane X receptor-mediated CYP3A4 gene expression in HepG2 liver carcinoma cellsBHLHB3: a candidate tumor suppressor in lung cancer.A systems approach defining constraints of the genome architecture on lineage selection and evolvability during somatic cancer evolutionCyclin E1 controls proliferation of hepatic stellate cells and is essential for liver fibrogenesis in mice.Preventing DNA over-replication: a Cdk perspective.E2f3a and E2f3b make overlapping but different contributions to total E2f3 activity.Loss of Cdk2 and Cdk4 induces a switch from proliferation to differentiation in neural stem cells.Paternal Benzo[a]pyrene Exposure Modulates MicroRNA Expression Patterns in the Developing Mouse Embryo.PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells.Cyclin-dependent kinase activity is required for type I interferon production.Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells.Molecular mechanisms of cellular senescence and immortalization of human cells.Structural insights into the functional diversity of the CDK-cyclin family
P2860
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P2860
Cell-specific responses to loss of cyclin-dependent kinases.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Cell-specific responses to loss of cyclin-dependent kinases.
@ast
Cell-specific responses to loss of cyclin-dependent kinases.
@en
type
label
Cell-specific responses to loss of cyclin-dependent kinases.
@ast
Cell-specific responses to loss of cyclin-dependent kinases.
@en
prefLabel
Cell-specific responses to loss of cyclin-dependent kinases.
@ast
Cell-specific responses to loss of cyclin-dependent kinases.
@en
P2860
P356
P1433
P1476
Cell-specific responses to loss of cyclin-dependent kinases
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210243
P407
P577
2007-02-05T00:00:00Z