Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo.
about
Eukaryotic translesion polymerases and their roles and regulation in DNA damage toleranceA rescue act: Translesion DNA synthesis past N(2) -deoxyguanosine adductsMass spectrometry for the assessment of the occurrence and biological consequences of DNA adductsAn active site aromatic triad in Escherichia coli DNA Pol IV coordinates cell survival and mutagenesis in different DNA damaging agentsA chemical genetics analysis of the roles of bypass polymerase DinB and DNA repair protein AlkB in processing N2-alkylguanine lesions in vivoEfficient formation of the tandem thymine glycol/8-oxo-7,8-dihydroguanine lesion in isolated DNA and the mutagenic and cytotoxic properties of the tandem lesions in Escherichia coli cells.High-throughput analysis of the mutagenic and cytotoxic properties of DNA lesions by next-generation sequencing.Quantification of N2-carboxymethyl-2'-deoxyguanosine in calf thymus DNA and cultured human kidney epithelial cells by capillary high-performance liquid chromatography-tandem mass spectrometry coupled with stable isotope dilution methodRole of the DinB homologs Rv1537 and Rv3056 in Mycobacterium tuberculosisReplication and repair of a reduced 2΄-deoxyguanosine-abasic site interstrand cross-link in human cells.Cytotoxic and mutagenic properties of regioisomeric O²-, N3- and O⁴-ethylthymidines in bacterial cells.Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coliStructural and dynamic characterization of polymerase κ's minor groove lesion processing reveals how adduct topology impacts fidelity.Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenineSyntheses and characterizations of the in vivo replicative bypass and mutagenic properties of the minor-groove O2-alkylthymidine lesions.6-Thioguanine and S⁶-methylthioguanine are mutagenic in human cellsThe DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant.Translesion DNA Synthesis.The roles of DNA polymerases κ and ι in the error-free bypass of N2-carboxyalkyl-2'-deoxyguanosine lesions in mammalian cells.Mutagenic and cytotoxic properties of oxidation products of 5-methylcytosine revealed by next-generation sequencing.Escherichia coli YafP protein modulates DNA damaging property of the nitroaromatic compoundsIn vitro replication studies of carboxymethylated DNA lesions with Saccharomyces cerevisiae polymerase η.Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivoNoncognate DNA damage prevents the formation of the active conformation of the Y-family DNA polymerases DinB and DNA polymerase κInteractions and Localization of Escherichia coli Error-Prone DNA Polymerase IV after DNA Damage.Evidence for roles of the Escherichia coli Hda protein beyond regulatory inactivation of DnaA.Escherichia coli UmuC active site mutants: effects on translesion DNA synthesis, mutagenesis and cell survival.Accurate and efficient bypass of 8,5'-cyclopurine-2'-deoxynucleosides by human and yeast DNA polymerase η.Cytotoxic and mutagenic properties of O4-alkylthymidine lesions in Escherichia coli cells.In-vitro replication studies on O(2)-methylthymidine and O(4)-methylthymidineA quantitative assay for assessing the effects of DNA lesions on transcriptionQuantitative measurement of transcriptional inhibition and mutagenesis induced by site-specifically incorporated DNA lesions in vitro and in vivoChemical structure and properties of interstrand cross-links formed by reaction of guanine residues with abasic sites in duplex DNAA single residue unique to DinB-like proteins limits formation of the polymerase IV multiprotein complex in Escherichia coli.In vivo detection and replication studies of α-anomeric lesions of 2'-deoxyribonucleosides.Chemical synthesis of oligodeoxyribonucleotides containing N3- and O4-carboxymethylthymidine and their formation in DNADinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli.Nucleotide excision repair is a predominant mechanism for processing nitrofurazone-induced DNA damage in Escherichia coliA model for DNA polymerase switching involving a single cleft and the rim of the sliding clampMass Spectrometry-Based Quantitative Strategies for Assessing the Biological Consequences and Repair of DNA Adducts.
P2860
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P2860
Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Efficient and accurate bypass ...... lymerase in vitro and in vivo.
@ast
Efficient and accurate bypass ...... lymerase in vitro and in vivo.
@en
type
label
Efficient and accurate bypass ...... lymerase in vitro and in vivo.
@ast
Efficient and accurate bypass ...... lymerase in vitro and in vivo.
@en
prefLabel
Efficient and accurate bypass ...... lymerase in vitro and in vivo.
@ast
Efficient and accurate bypass ...... lymerase in vitro and in vivo.
@en
P2093
P2860
P356
P1476
Efficient and accurate bypass ...... olymerase in vitro and in vivo
@en
P2093
Haizheng Hong
Huachuan Cao
Yinsheng Wang
P2860
P304
P356
10.1073/PNAS.0711546105
P407
P577
2008-06-17T00:00:00Z