Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene
about
Biomedical and clinical promises of human pluripotent stem cells for neurological disordersTranslesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iotaRad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrestMouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesisSeparate roles of structured and unstructured regions of Y-family DNA polymerasesEukaryotic translesion polymerases and their roles and regulation in DNA damage tolerancePoleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cellsHuman Embryonic Stem Cells: A Model for the Study of Neural Development and Neurological DiseasesRole of DNA polymerase κ in the maintenance of genomic stabilityStructural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear AntigenRole of Human DNA Polymerase κ in Extension Opposite from a cis–syn Thymine DimerMultifaceted Recognition of Vertebrate Rev1 by Translesion Polymerases ζ and κMammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cellsInteraction of hREV1 with three human Y-family DNA polymerasesDNA polymerase eta participates in the mutagenic bypass of adducts induced by benzo[a]pyrene diol epoxide in mammalian cellsRole of PCNA and TLS polymerases in D-loop extension during homologous recombination in humansThe vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled siteThe N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesionsCrystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymeraseTwo-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammalsStructural and dynamic characterization of polymerase κ's minor groove lesion processing reveals how adduct topology impacts fidelity.Interplay of DNA repair, homologous recombination, and DNA polymerases in resistance to the DNA damaging agent 4-nitroquinoline-1-oxide in Escherichia coli.Redundancy of mammalian Y family DNA polymerases in cellular responses to genomic DNA lesions induced by ultraviolet lightTranslesion DNA polymerasesRev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation.A human-specific TNF-responsive promoter for Goodpasture antigen-binding protein.The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa.Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations.Mouse DNA polymerase kappa has a functional role in the repair of DNA strand breaksThe roles of DNA polymerases κ and ι in the error-free bypass of N2-carboxyalkyl-2'-deoxyguanosine lesions in mammalian cells.Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sitesStructure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic featuresTP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts.Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability.Beyond translesion synthesis: polymerase κ fidelity as a potential determinant of microsatellite stability.What a difference a decade makes: insights into translesion DNA synthesis.Replication of damaged DNA by translesion synthesis in human cells.Translesion DNA polymerases and cancerSuffering in silence: the tolerance of DNA damage.Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells.
P2860
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P2860
Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Polkappa protects mammalian ce ...... enic effects of benzo[a]pyrene
@ast
Polkappa protects mammalian ce ...... enic effects of benzo[a]pyrene
@en
Polkappa protects mammalian ce ...... enic effects of benzo[a]pyrene
@nl
type
label
Polkappa protects mammalian ce ...... enic effects of benzo[a]pyrene
@ast
Polkappa protects mammalian ce ...... enic effects of benzo[a]pyrene
@en
Polkappa protects mammalian ce ...... enic effects of benzo[a]pyrene
@nl
prefLabel
Polkappa protects mammalian ce ...... enic effects of benzo[a]pyrene
@ast
Polkappa protects mammalian ce ...... enic effects of benzo[a]pyrene
@en
Polkappa protects mammalian ce ...... enic effects of benzo[a]pyrene
@nl
P2093
P2860
P356
P1476
Polkappa protects mammalian ce ...... enic effects of benzo[a]pyrene
@en
P2093
Haruo Ohmori
Kiyoji Tanaka
Yoichi Shinkai
P2860
P304
15548-15553
P356
10.1073/PNAS.222377899
P407
P50
P577
2002-11-13T00:00:00Z