A small-molecule E2F inhibitor blocks growth in a melanoma culture model.
about
RB1: a prototype tumor suppressor and an enigmaE2F4 Promotes Neuronal Regeneration and Functional Recovery after Spinal Cord Injury in ZebrafishArf induction by Tgfβ is influenced by Sp1 and C/ebpβ in opposing directionsRegulation of CHK1 by mTOR contributes to the evasion of DNA damage barrier of cancer cellsThe antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death.E2F inhibition synergizes with paclitaxel in lung cancer cell linesA complex task? Direct modulation of transcription factors with small molecules.Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant MelanomaE2F1 and E2F2 prevent replicative stress and subsequent p53-dependent organ involution.Classic "broken cell" techniques and newer live cell methods for cell cycle assessmentEstablished and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation.Antitumor and modeling studies of a penetratin-peptide that targets E2F-1 in small cell lung cancer.A novel peptide that inhibits E2F transcription and regresses prostate tumor xenografts.Therapeutical potential of deregulated lysine methyltransferase SMYD3 as a safe target for novel anticancer agents.The stress of coping with E2F lossInhibition of Skp2 sensitizes lung cancer cells to paclitaxel.E2F1-mediated human POMC expression in ectopic Cushing's syndrome.E2F/DP Prevents Cell-Cycle Progression in Endocycling Fat Body Cells by Suppressing dATM Expression.BRD4 regulates cellular senescence in gastric cancer cells via E2F/miR-106b/p21 axis.EGFR Induces E2F1-Mediated Corticotroph Tumorigenesis.E2F signature is predictive for the pancreatic adenocarcinoma clinical outcome and sensitivity to E2F inhibitors, but not for the response to cytotoxic-based treatments.E2F1 inhibition mediates cell death of metastatic melanoma.Cell Cycle Regulators and Lineage-Specific Therapeutic Targets for Cushing Disease
P2860
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P2860
A small-molecule E2F inhibitor blocks growth in a melanoma culture model.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A small-molecule E2F inhibitor blocks growth in a melanoma culture model.
@ast
A small-molecule E2F inhibitor blocks growth in a melanoma culture model.
@en
type
label
A small-molecule E2F inhibitor blocks growth in a melanoma culture model.
@ast
A small-molecule E2F inhibitor blocks growth in a melanoma culture model.
@en
prefLabel
A small-molecule E2F inhibitor blocks growth in a melanoma culture model.
@ast
A small-molecule E2F inhibitor blocks growth in a melanoma culture model.
@en
P2093
P2860
P1433
P1476
A small-molecule E2F inhibitor blocks growth in a melanoma culture model.
@en
P2093
Courtney A Kurtyka
Harshani Lawrence
Sandhya Boyapalle
Shen-Shu Sung
W Douglas Cress
Wayne Guida
P2860
P304
P356
10.1158/0008-5472.CAN-08-0121
P407
P577
2008-08-01T00:00:00Z