Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined "Complementary Lethality". - Wikidata - awgldk - TriplyDB

Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined "Complementary Lethality".

Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined "Complementary Lethality".

http://www.wikidata.org/entity/Q36738376

about

Transcriptional profiling and dynamical regulation analysis identify potential kernel target genes of SCYL1-BP1 in HEK293T cells.Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous Recombination Knocking Down TMPRSS2-ERG Fusion Oncogene by siRNA Could be an Alternative Treatment to Flutamide Inhibition of uracil DNA glycosylase sensitizes cancer cells to 5-fluorodeoxyuridine through replication fork collapse-induced DNA damage.Targeting homologous recombination-mediated DNA repair in cancer.Albumin-drug conjugates in the treatment of hepatic disorders.BRCA2 inhibition enhances cisplatin-mediated alterations in tumor cell proliferation, metabolism, and metastasis.Indoleamine 2,3-dioxygenase mediates immune-independent human tumor cell resistance to olaparib, gamma radiation, and cisplatin Evaluating the effectiveness of cancer drug sensitization in vitro and in vivo.

P2860

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P2860

Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined "Complementary Lethality".

http://www.wikidata.org/entity/Q36738376

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Inhibition of BRCA2 and Thymid ...... ned "Complementary Lethality".

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Inhibition of BRCA2 and Thymid ...... ned "Complementary Lethality".

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type

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Inhibition of BRCA2 and Thymid ...... ned "Complementary Lethality".

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Inhibition of BRCA2 and Thymid ...... ned "Complementary Lethality".

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Inhibition of BRCA2 and Thymid ...... ned "Complementary Lethality".

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Inhibition of BRCA2 and Thymid ...... ned "Complementary Lethality".

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Molecular therapy. Nucleic acids

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Inhibition of BRCA2 and Thymid ...... ned "Complementary Lethality".

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P2093

James Koropatnick

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Mark Vincent

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Mateusz Rytelewski

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Peter J Ferguson

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Rene Figueredo

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Saman Maleki Vareki

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P2860

Purified human BRCA2 stimulates RAD51-mediated recombination

The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51

Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein

A comprehensive catalogue of somatic mutations from a human cancer genome

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer

Unraveling the mechanism of BRCA2 in homologous recombination

Protein tolerance to random amino acid change

Antisense-induced down-regulation of thymidylate synthase and enhanced cytotoxicity of 5-FUdR in 5-FUdR-resistant HeLa cells

Identification of the breast cancer susceptibility gene BRCA2

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10.1038/MTNA.2013.7

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2

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2013-03-12T00:00:00Z

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