Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies - Wikidata - awgldk - TriplyDB

Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies

Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies

http://www.wikidata.org/entity/Q36740470

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Erythropoietin and diabetes mellitus Erythropoietin: new directions for the nervous system Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin Erythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life Expectancy Novel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic disease Optimal neuroprotection by erythropoietin requires elevated expression of its receptor in neurons A new agonist of the erythropoietin receptor, Epobis, induces neurite outgrowth and promotes neuronal survival Age-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations.Otoprotective effects of erythropoietin on Cdh23erl/erl mice FoxO3a governs early microglial proliferation and employs mitochondrial depolarization with caspase 3, 8, and 9 cleavage during oxidant induced apoptosis.Oxidative stress: Biomarkers and novel therapeutic pathways.New strategies for Alzheimer's disease and cognitive impairment.Diabetes mellitus: channeling care through cellular discovery Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment.FOXO3a governs early and late apoptotic endothelial programs during elevated glucose through mitochondrial and caspase signaling.The "O" class: crafting clinical care with FoxO transcription factors.Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation.Wnt1, FoxO3a, and NF-kappaB oversee microglial integrity and activation during oxidant stress.Wnt1 neuroprotection translates into improved neurological function during oxidant stress and cerebral ischemia through AKT1 and mitochondrial apoptotic pathways.PRAS40 is an integral regulatory component of erythropoietin mTOR signaling and cytoprotection Perinatal hypoxic-ischemic encephalopathy.Novel avenues of drug discovery and biomarkers for diabetes mellitus.Standardized environmental enrichment supports enhanced brain plasticity in healthy rats and prevents cognitive impairment in epileptic rats.Generation of biologically active multi-sialylated recombinant human EPOFc in plants.EPO relies upon novel signaling of Wnt1 that requires Akt1, FoxO3a, GSK-3β, and β-catenin to foster vascular integrity during experimental diabetes.High-dose erythropoietin in acute ST-segment elevation myocardial infarction: a meta-analysis of randomized controlled trials.Erythropoietin-derived nonerythropoietic peptide ameliorates experimental autoimmune neuritis by inflammation suppression and tissue protection.Erythropoietin employs cell longevity pathways of SIRT1 to foster endothelial vascular integrity during oxidant stress.Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders.Isotretinoin and FoxO1: A scientific hypothesis.Translating cell survival and cell longevity into treatment strategies with SIRT1 Targeting cardiovascular disease with novel SIRT1 pathways.Erythropoietin and Wnt1 govern pathways of mTOR, Apaf-1, and XIAP in inflammatory microglia.SIRT1: new avenues of discovery for disorders of oxidative stress Prevention of β-amyloid degeneration of microglia by erythropoietin depends on Wnt1, the PI 3-K/mTOR pathway, Bad, and Bcl-xL.Regeneration in the nervous system with erythropoietin Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascade Novel directions for diabetes mellitus drug discovery Charting a course for erythropoietin in traumatic brain injury.Erythropoietin and oxidative stress.

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Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies

http://www.wikidata.org/entity/Q36740470

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2008 nî lūn-bûn

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies

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Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies

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type

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Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies

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Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies

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Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies

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Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies

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J.PNEUROBIO.2008.02.002

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Progress in Neurobiology

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Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies

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Faqi Li

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Kenneth Maiese

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Yan Chen Shang

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Zhao Zhong Chong

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P2860

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

Isolation and characterization of genomic and cDNA clones of human erythropoietin

Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase

Elevation of cellular NAD levels by nicotinic acid and involvement of nicotinic acid phosphoribosyltransferase in human cells

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

One hundred years of hormones

Cloning and expression of the human erythropoietin gene

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10.1016/J.PNEUROBIO.2008.02.002

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2

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