Smurf2 regulates the senescence response and suppresses tumorigenesis in mice. - Wikidata - awgldk - TriplyDB

Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.

Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.

http://www.wikidata.org/entity/Q36740590

about

miRNA-200c inhibits invasion and metastasis of human non-small cell lung cancer by directly targeting ubiquitin specific peptidase 25 The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness.Smurf2 regulates hematopoietic stem cell self-renewal and aging.Skeletal Characterization of Smurf2-Deficient Mice and In Vitro Analysis of Smurf2-Deficient Chondrocytes A Circulating microRNA Signature Predicts Age-Based Development of Lymphoma.Effect of SMURF2 targeting on susceptibility to MEK inhibitors in melanoma.Smurf2 suppresses B-cell proliferation and lymphomagenesis by mediating ubiquitination and degradation of YY1.Downregulation of Smurf2, a tumor-suppressive ubiquitin ligase, in triple-negative breast cancers: involvement of the RB-microRNA axis.SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts Role of the ubiquitin proteasome system in hematologic malignancies.The impact of TEL-AML1 (ETV6-RUNX1) expression in precursor B cells and implications for leukaemia using three different genome-wide screening methods.YY1 Regulates the Germinal Center Reaction by Inhibiting Apoptosis.Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis.Challenges for Super-Resolution Localization Microscopy and Biomolecular Fluorescent Nano-Probing in Cancer Research.Smurf2 regulates stability and the autophagic-lysosomal turnover of lamin A and its disease-associated form progerin.Smurfs in Protein Homeostasis, Signaling, and Cancer

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P2860

Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.

http://www.wikidata.org/entity/Q36740590

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

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2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.

@ast

Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.

@en

type

label

Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.

@ast

Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.

@en

prefLabel

Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.

@ast

Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.

@en

P1433

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0008-5472.CAN-11-3773

P1433

Cancer Research

P1476

Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.

@en

P2093

Charusheila Ramkumar

http://www.w3.org/2001/XMLSchema#string

Hang Cui

http://www.w3.org/2001/XMLSchema#string

Hong Zhang

http://www.w3.org/2001/XMLSchema#string

Rachel M Gerstein

http://www.w3.org/2001/XMLSchema#string

Stephen N Jones

http://www.w3.org/2001/XMLSchema#string

Suyang Hao

http://www.w3.org/2001/XMLSchema#string

Yahui Kong

http://www.w3.org/2001/XMLSchema#string

P2860

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3

Regulation of planar cell polarity by Smurf ubiquitin ligases

Smurf2 up-regulation activates telomere-dependent senescence

Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity

Id family of helix-loop-helix proteins in cancer

Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

P304

2714-2719

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scholarly article

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10.1158/0008-5472.CAN-11-3773

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11

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72

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2012-05-02T00:00:00Z

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22552287

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3616636

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