The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease. - Wikidata - awgldk - TriplyDB

The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease.

The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease.

http://www.wikidata.org/entity/Q36745053

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Pyruvate Kinase M2: A Potential Target for Regulating Inflammation Diabetes propels the risk for cardiovascular disease: sweet monocytes becoming aggressive?TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.SOCS1 is a negative regulator of metabolic reprogramming during sepsis Homocysteine Activates B Cells via Regulating PKM2-Dependent Metabolic Reprogramming.Metabolic Factors that Contribute to Lupus Pathogenesis Mitochondrial PKM2 regulates oxidative stress-induced apoptosis by stabilizing Bcl2.Applying nanomedicine in maladaptive inflammation and angiogenesis.Macrophage metabolism in atherosclerosis.Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction.A guide to immunometabolism for immunologists.Immune Cell Metabolism in Systemic Lupus Erythematosus.Metabolic regulation of inflammation.Immunometabolism in early and late stages of rheumatoid arthritis.Metabolic signatures of T-cells and macrophages in rheumatoid arthritis.Similarities and Distinctions of Cancer and Immune Metabolism in Inflammation and Tumors.Regulation of Metabolism Across Different Subsets of T Cells in Cancer.Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites.Pyruvate controls the checkpoint inhibitor PD-L1 and suppresses T cell immunity.Elevated serum interleukin-6 is predictive of coronary artery disease in intermediate risk overweight patients referred for coronary angiography.Epigenetics and trained immunity.Immunoinhibitory checkpoint deficiency in medium and large vessel vasculitis.Pyruvate Kinase M2 Is Required for the Expression of the Immune Checkpoint PD-L1 in Immune Cells and Tumors.Plasma TuM2-PK correlates with tumor size, CRP and CA 15-3 in metastatic breast carcinomas; short versus long term follow up study of the Egyptian breast cancer patients.Metabolic control of the scaffold protein TKS5 in tissue-invasive, proinflammatory T cells.Efficacy of Shikonin against Esophageal Cancer Cells and its possible mechanisms in vitro and in vivo.Rutin inhibits coronary heart disease through ERK1/2 and Akt signaling in a porcine model.Exploring Non-Metabolic Functions of Glycolytic Enzymes in Immunity.Lack of myeloid Fatp1 increases atherosclerotic lesion size in Ldlr-/- mice.Monocyte-Macrophages and T Cells in Atherosclerosis.Monocyte and macrophage immunometabolism in atherosclerosis.Role of SLC7A5 in Metabolic Reprogramming of Human Monocyte/Macrophage Immune Responses.New Insights into the Immunobiology of Mononuclear Phagocytic Cells and Their Relevance to the Pathogenesis of Cardiovascular Diseases.Endothelial Cell Metabolism.Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity.Metabolic reprogramming in the pathogenesis of chronic lung diseases including BPD, COPD, and pulmonary fibrosis.Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.Enhanced glycolysis contributes to the pathogenesis of experimental autoimmune neuritis.The Potential Role of Trained Immunity in Autoimmune and Autoinflammatory Disorders.Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques.

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The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease.

http://www.wikidata.org/entity/Q36745053

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2016 nî lūn-bûn

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

The glycolytic enzyme PKM2 bri ...... on in coronary artery disease.

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The glycolytic enzyme PKM2 bri ...... on in coronary artery disease.

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The glycolytic enzyme PKM2 bri ...... on in coronary artery disease.

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The glycolytic enzyme PKM2 bri ...... on in coronary artery disease.

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The glycolytic enzyme PKM2 bri ...... on in coronary artery disease.

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The glycolytic enzyme PKM2 bri ...... on in coronary artery disease.

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P1433

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Journal of Experimental Medicine

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The glycolytic enzyme PKM2 bri ...... on in coronary artery disease.

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P2093

Barbara B Wallis

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Cornelia M Weyand

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David G Harrison

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John C Giacomini

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Jörg J Goronzy

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Lu Tian

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Rafal R Nazarewicz

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Rolando E Yanes

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P2860

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

SAICAR induces protein kinase activity of PKM2 that is necessary for sustained proliferative signaling of cancer cells

Effects of tempol and redox-cycling nitroxides in models of oxidative stress.

Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: meta-analysis of randomised controlled trials

Update on Prevention of Cardiovascular Disease in Adults With Type 2 Diabetes Mellitus in Light of Recent Evidence: A Scientific Statement From the American Heart Association and the American Diabetes Association

Macrophages in vascular inflammation--From atherosclerosis to vasculitis

The influence of innate and adaptive immune responses on atherosclerosis

Beyond oxidative stress: an immunologist's guide to reactive oxygen species

Immune activation caused by vascular oxidation promotes fibrosis and hypertension

Pyruvate kinase M2 is a phosphotyrosine-binding protein

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337-354

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scholarly article

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10.1084/JEM.20150900

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P433

3

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213

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Themistocles L Assimes

Tsuyoshi Shirai

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2016-02-29T00:00:00Z

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26926996

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P932

4813677

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