about
The crystal structure of Toxoplasma gondii pyruvate kinase 1Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage responseThe metabolic advantage of tumor cellsIdentification of small molecule inhibitors of pyruvate kinase M2Phosphofructokinase 1 glycosylation regulates cell growth and metabolismStructure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherinDeath-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinaseDominant negative mutations affect oligomerization of human pyruvate kinase M2 isozyme and promote cellular growth and polyploidyUnderstanding the Warburg effect: the metabolic requirements of cell proliferationNo evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesisHuman pyruvate kinase M2: a multifunctional proteinDifferential behavior of missense mutations in the intersubunit contact domain of the human pyruvate kinase M2 isozymeNovel drugs that target the metabolic reprogramming in renal cell cancerAnticancer strategies based on the metabolic profile of tumor cells: therapeutic targeting of the Warburg effectInterplay Between Metabolism and Oncogenic Process: Role of microRNAsPyruvate kinase: Function, regulation and role in cancerIs cancer a metabolic disease?Rho GTPases and their roles in cancer metabolismPyruvate kinase M2 at a glanceAdaptations of energy metabolism during cerebellar neurogenesis are co-opted in medulloblastomaFueling immunity: insights into metabolism and lymphocyte functionAllosteric Mechanism of Pyruvate Kinase from Leishmania mexicana Uses a Rock and Lock ModelAn improved strategy for the crystallization ofLeishmania mexicanapyruvate kinasePyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesisSmall Molecule Activation of PKM2 in Cancer Cells Induces Serine AuxotrophySerine is a natural ligand and allosteric activator of pyruvate kinase M2M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation.`In crystallo' substrate binding triggers major domain movements and reveals magnesium as a co-activator of Trypanosoma brucei pyruvate kinaseMetabolic reprogramming in cancer cells: glycolysis, glutaminolysis, and Bcl-2 proteins as novel therapeutic targets for cancerThe HK2 Dependent "Warburg Effect" and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-BromopyruvateROS homeostasis and metabolism: a critical liaison for cancer therapyA human short open reading frame (sORF)-encoded polypeptide that stimulates DNA end joiningA DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effectThe language of SH2 domain interactions defines phosphotyrosine-mediated signal transductionAlternative pre-mRNA splicing regulation in cancer: pathways and programs unhingedRegulation of PKM2 and Nrf2-ARE pathway during benzoquinone induced oxidative stress in yolk sac hematopoietic stem cellsFor glioma, a sweet side to diabetesEpithelial cancers in the post-genomic era: should we reconsider our lifestyle?Evaluation of toxicogenomics approaches for assessing the risk of nongenotoxic carcinogenicity in rat liverDifferentially expressed proteins in malignant and benign adrenocortical tumors
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Pyruvate kinase M2 is a phosphotyrosine-binding protein
@ast
Pyruvate kinase M2 is a phosphotyrosine-binding protein
@en
Pyruvate kinase M2 is a phosphotyrosine-binding protein
@nl
type
label
Pyruvate kinase M2 is a phosphotyrosine-binding protein
@ast
Pyruvate kinase M2 is a phosphotyrosine-binding protein
@en
Pyruvate kinase M2 is a phosphotyrosine-binding protein
@nl
prefLabel
Pyruvate kinase M2 is a phosphotyrosine-binding protein
@ast
Pyruvate kinase M2 is a phosphotyrosine-binding protein
@en
Pyruvate kinase M2 is a phosphotyrosine-binding protein
@nl
P2093
P3181
P356
P1433
P1476
Pyruvate kinase M2 is a phosphotyrosine-binding protein
@en
P2093
John M Asara
Matthew G Vander Heiden
P2888
P3181
P356
10.1038/NATURE06667
P407
P577
2008-03-13T00:00:00Z
P5875
P6179
1030770844