The evolving role of drug metabolism in drug discovery and development.

The evolving role of drug metabolism in drug discovery and development.

Item
http://www.wikidata.org/entity/Q36749461
Advances in computationally modeling human oral bioavailabilityA chiral liquid chromatography method for the simultaneous determination of oxcarbazepine, eslicarbazepine, R-licarbazepine and other new chemical derivatives BIA 2-024, BIA 2-059 and BIA 2-265, in mouse plasma and brain.Liquid chromatography/quadrupole time-of-flight mass spectrometry in combination with online hydrogen/deuterium exchange technique for structural elucidation of phase I metabolites of iso-phenylcyclopentylamine in rat bile.Application of a liquid chromatography-tandem mass spectrometry method to the pharmacokinetics, tissue distribution and excretion in the study of anemoside B4, a novel antiviral agent candidate, in rats.The effect of oral lipids and circulating lipoproteins on the metabolism of drugs.Renal clearance in drug discovery and development: molecular descriptors, drug transporters and disease state.Preclinical in vivo ADME studies in drug development: a critical review.Comparative metabolism as a key driver of wildlife species sensitivity to human and veterinary pharmaceuticals.Modeling bioavailability to organs protected by biological barriers.Interspecies Variation of In Vitro Stability and Metabolic Diversity of YZG-331, a Promising Sedative-Hypnotic Compound.Validation of cell-based OATP1B1 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.The use of isolated enterocytes to study Phase I intestinal drug metabolism: validation with rat and pig intestine.Metabolism elucidation of BJ-B11 (a heat shock protein 90 inhibitor) by human liver microsomes: identification of main contributing enzymes.
P2860

The evolving role of drug metabolism in drug discovery and development.

Item
http://www.wikidata.org/entity/Q36749461
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The evolving role of drug metabolism in drug discovery and development.
@en
type
label
The evolving role of drug metabolism in drug discovery and development.
@en
prefLabel
The evolving role of drug metabolism in drug discovery and development.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
The evolving role of drug metabolism in drug discovery and development.
@en
P2093
P304
P31
P356
P433
P478
P577
P698