Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary - Wikidata - awgldk - TriplyDB

Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary

Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary

http://www.wikidata.org/entity/Q36753781

about

Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses.Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis.Local protease signaling contributes to neural tube closure in the mouse embryo Tumor detection by imaging proteolytic activity Transport via the transcytotic pathway makes prostasin available as a substrate for matriptase Detection of active matriptase using a biotinylated chloromethyl ketone peptide Matriptase is inhibited by extravascular antithrombin in epithelial cells but not in most carcinoma cells Hepatocyte growth factor activator inhibitor-2 prevents shedding of matriptase Prostasin is required for matriptase activation in intestinal epithelial cells to regulate closure of the paracellular pathway.Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition.Membrane-bound serine protease inhibitor HAI-1 is required for maintenance of intestinal epithelial integrity.Loss of membrane-bound serine protease inhibitor HAI-1 induces oral squamous cell carcinoma cells' invasiveness.Matriptase does not require hepatocyte growth factor activator inhibitor type-1 for activation in an epithelial cell expression model.Involvement of the cytoplasmic juxtamembrane region of matriptase in its exclusive localization to the basolateral membrane domain of Madin-Darby canine kidney epithelial cells.Annexin A2 regulates angiogenesis and invasion phenotypes of malignant glioma.Hepatocyte growth factor activator inhibitor type 1 inhibits protease activity and proteolytic activation of human airway trypsin-like protease.Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion.HAI-2 stabilizes, inhibits and regulates SEA-cleavage-dependent secretory transport of matriptase.

P2860

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P2860

Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary

http://www.wikidata.org/entity/Q36753781

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary

@en

type

label

Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary

@en

prefLabel

Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary

@en

P1433

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P1433

Biochemical Journal

P1476

Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary

@en

P2093

Esben D K Pedersen

http://www.w3.org/2001/XMLSchema#string

Joanna Selzer-Plon

http://www.w3.org/2001/XMLSchema#string

Kathrine Abell

http://www.w3.org/2001/XMLSchema#string

Lotte K Vogel

http://www.w3.org/2001/XMLSchema#string

Roman Szabo

http://www.w3.org/2001/XMLSchema#string

Sine Godiksen

http://www.w3.org/2001/XMLSchema#string

P2860

Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation

Hepatocyte growth factor activator inhibitor, a novel Kunitz-type serine protease inhibitor

Human meprin beta: O-linked glycans in the intervening region of the type I membrane protein protect the C-terminal region from proteolytic cleavage and diminish its secretion

Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo

Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk

Distribution of hepatocyte growth factor activator inhibitor type 1 (HAI-1) in human tissues. Cellular surface localization of HAI-1 in simple columnar epithelium and its modulated expression in injured and regenerative tissues

Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease

Multiple sites of proteolytic cleavage to release soluble forms of hepatocyte growth factor activator inhibitor type 1 from a transmembrane form

The activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitor

P304

251-259

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P31

scholarly article

P356

10.1042/BJ20071496

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P407

P433

2

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P478

413

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P50

Hanne B. Rasmussen

Thomas H. Bugge

P577

2008-07-01T00:00:00Z

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P698

18402552

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P932

4816720

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