Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival
about
The PI3K signaling pathway as a pharmacological target in Autism related disorders and Schizophrenia.HLA-DRα1-mMOG-35-55 treatment of experimental autoimmune encephalomyelitis reduces CNS inflammation, enhances M2 macrophage frequency, and promotes neuroprotection.Fibroblast Growth Factor Receptor-2 Contributes to the Basic Fibroblast Growth Factor-Induced Neuronal Differentiation in Canine Bone Marrow Stromal Cells via Phosphoinositide 3-Kinase/Akt Signaling PathwayAlternative Activation Mechanisms of Protein Kinase B Trigger Distinct Downstream Signaling Responses.Mutation of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) substrate-docking site in the developing brain causes microcephaly with abnormal brain morphogenesis independently of Akt, leading to impaired cognition and disruptive behaviors.Crosstalk between phosphodiesterase 7 and glycogen synthase kinase-3: two relevant therapeutic targets for neurological disorders.Fine-tuning the intensity of the PKB/Akt signal enables diverse physiological responses.Targeting PDK1 for Chemosensitization of Cancer Cells.Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides.Geometric Navigation of Axons in a Cerebral Pathway: Comparing dMRI with Tract Tracing and Immunohistochemistry.PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway.
P2860
Q26766054-076F16FF-3E65-40A9-93DE-1F1D5EC2D2E5Q35782781-0FA4CB68-F541-41E4-A1BE-EF4912526BA9Q35829120-F561A1DE-D44E-432D-A888-32AAF59435EDQ36139887-D2C19554-70B3-48F6-9CEF-6906A5F4B430Q37413675-020802DD-7958-4A7A-BC2B-5F1034F6BC1CQ37657490-F43DB940-F6A5-4AE9-A35E-3245EC8DFB18Q41902385-A9D770DB-625D-474D-9FCA-B960EA771A01Q43276810-CE2CF234-CD51-4A86-8F96-A46DDB6A2AC6Q47845996-1DE29D1B-4241-4B4F-9BC1-05BB6F678B47Q48306760-A88B5F4B-277E-4D1E-80E9-84964D00A6CBQ54119484-A36B4A27-5F4E-475B-8CEB-8071C6AC73A5
P2860
Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Interaction of PDK1 with phosp ...... pensable for neuronal survival
@ast
Interaction of PDK1 with phosp ...... pensable for neuronal survival
@en
type
label
Interaction of PDK1 with phosp ...... pensable for neuronal survival
@ast
Interaction of PDK1 with phosp ...... pensable for neuronal survival
@en
prefLabel
Interaction of PDK1 with phosp ...... pensable for neuronal survival
@ast
Interaction of PDK1 with phosp ...... pensable for neuronal survival
@en
P2093
P2860
P356
P1476
Interaction of PDK1 with phosp ...... pensable for neuronal survival
@en
P2093
Gerard Ruiz-Babot
Jose M Lizcano
Jose R Bayascas
Lluís Cordón-Barris
Lydia Giménez-Llort
Nestor Gómez
Tinatin Zurashvili
Xiangyu Zhou
P2860
P304
P356
10.1128/MCB.01052-12
P407
P577
2012-12-28T00:00:00Z