Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis
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Targeting MT1-MMP as an ImmunoPET-Based Strategy for Imaging GliomasThe role of lymphangiogenesis and angiogenesis in tumor metastasisProtein interference applications in cellular and developmental biology using DARPins that recognize GFP and mCherry.New strategies for targeting matrix metalloproteinasesMatrix metalloproteinases as breast cancer drivers and therapeutic targets.Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis.MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis.Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivoMatrix metalloproteinase 14 participates in corneal lymphangiogenesis through the VEGF-C/VEGFR-3 signaling pathway.A monoclonal antibody interferes with TIMP-2 binding and incapacitates the MMP-2-activating function of multifunctional, pro-tumorigenic MMP-14/MT1-MMP.Monitoring and Inhibiting MT1-MMP during Cancer Initiation and Progression.Targeting matrix metalloproteinase activity and expression for the treatment of viral myocarditis.Reciprocal relationship between membrane type 1 matrix metalloproteinase and the algesic peptides of myelin basic protein contributes to chronic neuropathic pain.Epigallocatechin gallate targeting of membrane type 1 matrix metalloproteinase-mediated Src and Janus kinase/signal transducers and activators of transcription 3 signaling inhibits transcription of colony-stimulating factors 2 and 3 in mesenchymal sTherapeutic Potential of Matrix Metalloproteinase Inhibition in Breast Cancer.MT-LOOP-dependent localization of membrane type I matrix metalloproteinase (MT1-MMP) to the cell adhesion complexes promotes cancer cell invasion.Matrix metalloproteinase 2 and membrane type 1 matrix metalloproteinase co-regulate axonal outgrowth of mouse retinal ganglion cells.MT1-MMP as a PET Imaging Biomarker for Pancreas Cancer Management
P2860
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P2860
Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Targeting a single function of ...... P: impact on lymphangiogenesis
@ast
Targeting a single function of ...... P: impact on lymphangiogenesis
@en
type
label
Targeting a single function of ...... P: impact on lymphangiogenesis
@ast
Targeting a single function of ...... P: impact on lymphangiogenesis
@en
prefLabel
Targeting a single function of ...... P: impact on lymphangiogenesis
@ast
Targeting a single function of ...... P: impact on lymphangiogenesis
@en
P2093
P2860
P50
P356
P1476
Targeting a single function of ...... P: impact on lymphangiogenesis
@en
P2093
Astrid Porse
Charlotte Erpicum
Gunilla Høyer-Hansen
Henrik Gårdsvoll
Henrik J Jürgensen
Kenn Holmbeck
Ludovic Maertens
Maria C Melander
P2860
P304
10195-10204
P356
10.1074/JBC.M112.447169
P407
P577
2013-02-14T00:00:00Z