Metabolome response to glucose in the β-cell line INS-1 832/13.
about
Metabolomics applied to the pancreatic isletSignaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cellsMetabolomics and diabetes: analytical and computational approachesBioluminescent cell-based NAD(P)/NAD(P)H assays for rapid dinucleotide measurement and inhibitor screening.Increased glucose metabolism and glycerolipid formation by fatty acids and GPR40 receptor signaling underlies the fatty acid potentiation of insulin secretionRelative quantification of amine-containing metabolites using isobaric N,N-dimethyl leucine (DiLeu) reagents via LC-ESI-MS/MS and CE-ESI-MS/MS.A role for cytosolic isocitrate dehydrogenase as a negative regulator of glucose signaling for insulin secretion in pancreatic ß-cells.Contact-induced clustering of syntaxin and munc18 docks secretory granules at the exocytosis site.Characterization of phospholipids in insulin secretory granules and mitochondria in pancreatic beta cells and their changes with glucose stimulation.Metabolomics Analysis Reveals that AICAR Affects Glycerolipid, Ceramide and Nucleotide Synthesis Pathways in INS-1 Cells.Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function.Evaluation of coverage, retention patterns, and selectivity of seven liquid chromatographic methods for metabolomics.Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.A comprehensive lipidomic screen of pancreatic β-cells using mass spectroscopy defines novel features of glucose-stimulated turnover of neutral lipids, sphingolipids and plasmalogensKnockdown of ATP citrate lyase in pancreatic beta cells does not inhibit insulin secretion or glucose flux and implicates the acetoacetate pathway in insulin secretionSum of the parts: mass spectrometry-based metabolomicsMetabolic fate of glucose and candidate signaling and excess-fuel detoxification pathways in pancreatic β-cells.Effects of Metformin and a Mammalian Target of Rapamycin (mTOR) ATP-Competitive Inhibitor on Targeted Metabolomics in Pancreatic Cancer Cell Line.Metabolomics and Metabolic Diseases: Where Do We Stand?Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism.Different responses of mouse islets and MIN6 pseudo-islets to metabolic stimulation: a note of caution.Glucose-stimulated single pancreatic islets sustain increased cytosolic ATP levels during initial Ca2+ influx and subsequent Ca2+ oscillations.Alpha TC1 and Beta-TC-6 genomic profiling uncovers both shared and distinct transcriptional regulatory features with their primary islet counterparts.Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle.Metabolomics applied to islet nutrient sensing mechanisms.Positive Feedback Amplifies the Response of Mitochondrial Membrane Potential to Glucose Concentration in Clonal Pancreatic Beta Cells.Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly.Role of G-proteins in islet function in health and diabetes.Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets.N-Acetylgalactosamine-Targeted Delivery of Dendrimer-Doxorubicin Conjugates Influences Doxorubicin Cytotoxicity and Metabolic Profile in Hepatic Cancer Cells.Identification of the signals for glucose-induced insulin secretion in INS1 (832/13) β-cells using metformin-induced metabolic deceleration as a model.
P2860
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P2860
Metabolome response to glucose in the β-cell line INS-1 832/13.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Metabolome response to glucose in the β-cell line INS-1 832/13.
@ast
Metabolome response to glucose in the β-cell line INS-1 832/13.
@en
type
label
Metabolome response to glucose in the β-cell line INS-1 832/13.
@ast
Metabolome response to glucose in the β-cell line INS-1 832/13.
@en
prefLabel
Metabolome response to glucose in the β-cell line INS-1 832/13.
@ast
Metabolome response to glucose in the β-cell line INS-1 832/13.
@en
P2860
P356
P1476
Metabolome response to glucose in the β-cell line INS-1 832/13.
@en
P2093
Mahmoud A El Azzouny
Matthew A Lorenz
P2860
P304
10923-10935
P356
10.1074/JBC.M112.414961
P407
P577
2013-02-20T00:00:00Z